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How to get fromFrankfurt(Main)Hbf to Sienaby plane, train, train (Trenitalia), bus, night train, or car

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There are 9 ways to get from Frankfurt(Main)Hbf to Siena by plane, train, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 10m
    €135–291

  2. Bus via Frankfurt central train station

    cheapest
    1. Take the bus from Frankfurt central train station to Florence Villa Constanza Bus Stationbus bus N77 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    18h 33m
    €95–160

  3. Train

    1. Take the train from Frankfurt to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h
    €148–832

  4. Bus

    1. Take the bus from Frankfurt am Main - Stuttgarter Straße to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    16h 41m

  5. Train, night train

    1. Take the train from Frankfurt to Hauptbahnhoftrain train 11 / ...
    2. Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    3. Take the train from Verona Porta Nuova to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    19h 9m
    €120–354

  6. Fly to Pisa International Airport, train

    1. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    6h 2m
    €119–270

  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 34m
    €117–286

  8. Fly to Venice Marco Polo Airport, train

    1. Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane plane FRA - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 14m
    €109–296

  9. Drive 1,022.6 km

    1. Drive from Frankfurt(Main)Hbf to Sienacar car 1,022.6 km
    9h 49m
    €160–231

Frankfurt(Main)Hbf to Siena by train

Calendar76Weekly Trains
Duration13hAverage Duration
Ticket€148Cheapest Price
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Questions & Answers

Map of how to get from Frankfurt(Main)Hbf to Siena.ExpandLaunch map view
  • Distance: 832.6 km
  • Duration: 6h 10m

What companies run services between Frankfurt(Main)Hbf, Germany and Siena, Italy?

You can take a train from Frankfurt to Siena via Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h. Alternatively, you can take a vehicle from Frankfurt(Main)Hbf to Siena via Frankfurt am Main - Stuttgarter Straße and Florence Villa Constanza Bus Station in around 16h 41m.

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