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How to get fromFrankfurt am Main to Domodossolaby train, bus, car, or plane

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There are 10 ways to get from Frankfurt am Main to Domodossola by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Frankfurt to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Domodossolatrain train Ec
    6h 40m
    €146–608

  2. Fly to Milano Malpensa Airport, bus

    cheapest
    1. Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane plane FRA - MXP
    2. Take the bus from Aeroporto Malpensa - Terminal 1 to Domodossola - Stazione Ferroviariabus bus
    5h 36m
    €62–174

  3. Bus

    1. Take the bus from Frankfurt central train station to Milanbus bus FlixBus N474
    2. Take the bus from Aeroporto Malpensa - Terminal 1 to Domodossola - Stazione Ferroviariabus bus 3
    12h 55m
    €67–104

  4. Drive 630.4 km

    1. Drive from Frankfurt am Main to Domodossolacar car 630.4 km
    6h 21m
    €98–142

  5. Fly to Zurich Airport, train

    1. Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane plane FRA - ZRH
    2. Take the train from Zürich HB to Domodossolatrain train
    5h 48m
    €171–476

  6. Train via Spiez

    1. Take the train from Frankfurt to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Spieztrain train Ic6 / ...
    3. Take the train from Spiez to Domodossolatrain train Ec / ...
    7h 2m
    €90–522

  7. Train via Zurich

    1. Take the train from Frankfurt to Zürich HBtrain train
    2. Take the train from Zürich HB to Locarnotrain train
    3. Take the train from Locarno FART to Domodossolatrain train 72 / ...
    11h 51m
    €117–200

  8. Fly to Basel, train

    1. Fly from Frankfurt (FRA) to Basel (BSL)plane plane FRA - BSL
    2. Take the train from Basel SBB to Domodossolatrain train
    6h 16m
    €191–550

  9. Fly to Milan Linate Airport, train

    1. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane plane FRA - LIN
    2. Take the train from Milano Centrale to Domodossolatrain train
    6h 29m
    €70–214

  10. Fly to Geneva International Airport, train

    1. Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane plane FRA - GVA
    2. Take the train from Genève-Aéroport to Brigtrain train
    8h 9m
    €205–486

Frankfurt am Main to Domodossola by train

Calendar15Weekly Trains
Duration6h 40mAverage Duration
Ticket€146Cheapest Price
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Questions & Answers

Map of how to get from Frankfurt am Main to Domodossola.ExpandLaunch map view
  • Distance: 572.2 km
  • Duration: 6h 40m

What companies run services between Frankfurt am Main, Germany and Domodossola, Italy?

You can take a train from Frankfurt to Domodossola via Basel SBB in around 6h 40m. Alternatively, you can take a bus from Frankfurt central train station to Domodossola - Stazione Ferroviaria via Milan and Aeroporto Malpensa - Terminal 1 in around 12h 55m.

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