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How to get fromFrankfurt am Main to Ispraby train, bus, ferry, car, or plane

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There are 9 ways to get from Frankfurt am Main to Ispra by train, bus, ferry, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Frankfurt to Luganotrain train Ec
    9h 10m
    €212–668

  2. Fly Frankfurt to Milan Linate Airport, train

    cheapest
    1. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane plane FRA - LIN
    2. Take the train from Milano Dateo to Varesetrain train
    6h 44m
    €49–154

  3. Bus, ferry

    1. Take the bus from Frankfurt central train station to Milanbus bus FlixBus N474
    2. Take the ferry from Arona to Angeraferry ferry 24 / ...
    13h 27m
    €72–115

  4. Drive 625.9 km

    1. Drive from Frankfurt am Main to Ispracar car 625.9 km
    6h 17m
    €97–140

  5. Fly Frankfurt to Milano Malpensa Airport, train, bus

    1. Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane plane FRA - MXP
    2. Take the train from Malpensa Aeroporto T1 to Varesetrain train
    3. Take the bus from Varese, V. Veneto 9 to Ispra, Mazzini 59,bancabus bus
    5h 41m

  6. Train via Basel

    1. Take the train from Frankfurt to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ic21 / ...
    9h 39m
    €83–663

  7. Train via Zurich

    1. Take the train from Frankfurt to Zürich HBtrain train
    2. Take the train from Zürich HB to Biascatrain train
    3. Take the train from Biasca to Varesetrain train S50
    12h 31m
    €103–178

  8. Fly Frankfurt to Zurich Airport, train, bus

    1. Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane plane FRA - ZRH
    2. Take the train from Zürich HB to Luganotrain train
    3. Take the train from Lugano to Varesetrain train
    4. Take the bus from Varese, V. Veneto 9 to Ispra, Mazzini 59,bancabus bus
    7h 33m

  9. Train to Stuttgart Airport, fly to Milano Malpensa Airport, train

    1. Take the train from Frankfurt to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Milano Malpensa Airport (MXP)plane plane STR - MXP
    3. Take the train from Malpensa Aeroporto T1 to Varesetrain train
    7h 22m
    €107–367

Frankfurt am Main to Ispra by train and bus

Calendar6Weekly Services
Duration9h 10mAverage Duration
Ticket€212Cheapest Price
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Questions & Answers

Map of how to get from Frankfurt am Main to Ispra.ExpandLaunch map view
  • Distance: 652.3 km
  • Duration: 9h 10m

What companies run services between Frankfurt am Main, Germany and Ispra, Italy?

Swiss Federal Railways (SBB CFF FFS) operates a train from Frankfurt to Lugano 6 times a week. Tickets cost €200–650 and the journey takes 6h 22m.

Airlines
Train operators
Bus operators
Ferry operators

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