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How to get fromFrankfurt am Main to Lisseby train, bus, car, or plane

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There are 9 ways to get from Frankfurt am Main to Lisse by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Arnhem

    best
    1. Take the train from Frankfurt to Arnhem Centraaltrain train 78
    2. Take the train from Arnhem Centraal to Schiphol Airport Train Stationtrain train Intercity
    5h 11m
    €78–298

  2. Bus

    cheapest
    1. Take the bus from Frankfurt central train station to Amsterdam Sloterdijkbus bus N61 / ...
    7h 50m
    €46–77

  3. Drive 450.4 km

    1. Drive from Frankfurt am Main to Lissecar car 450.4 km
    4h 47m
    €80–115

  4. Fly Frankfurt to Amsterdam Airport Schiphol

    1. Fly from Frankfurt (FRA) to Amsterdam Airport Schiphol (AMS)plane plane FRA - AMS
    4h 16m
    €129–293

  5. Train

    1. Take the train from Frankfurt to Utrecht Centraaltrain train Ice / ...
    2. Take the train from Utrecht Centraal to Leiden Centraaltrain train Sprinter / ...
    5h 16m
    €54–108

  6. Train #2

    1. Take the train from Frankfurt to Utrecht Centraaltrain train 43N
    2. Take the train from Utrecht Centraal to Schiphol Airport Train Stationtrain train Intercity / ...
    8h 22m
    €92–367

  7. Train to Düsseldorf International Airport, fly to Amsterdam Airport Schiphol

    1. Take the train from Frankfurt to Düsseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Amsterdam Airport Schiphol (AMS)plane plane DUS - AMS
    4h 44m
    €167–461

  8. Fly Frankfurt to Düsseldorf International Airport, train

    1. Fly from Frankfurt (FRA) to Düsseldorf International Airport (DUS)plane plane FRA - DUS
    2. Take the train from Duesseldorf Flughafen to Arnhem Centraaltrain train
    3. Take the train from Arnhem Centraal to Schiphol Airport Train Stationtrain train
    6h 28m
    €151–198

  9. Train to Stuttgart Airport, fly to Amsterdam Airport Schiphol

    1. Take the train from Frankfurt to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Amsterdam Airport Schiphol (AMS)plane plane STR - AMS
    6h 12m
    €164–430

Frankfurt am Main to Lisse by train and bus

Calendar44Weekly Services
Duration5h 11mAverage Duration
Ticket€78Cheapest Price
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Questions & Answers

Map of how to get from Frankfurt am Main to Lisse.ExpandLaunch map view
  • Distance: 464.1 km
  • Duration: 5h 11m

What companies run services between Frankfurt am Main, Germany and Lisse, Netherlands?

You can take a train from Frankfurt to Lisse, Vreewijk via Arnhem Centraal, Schiphol Airport, and Schiphol, Airport/Plaza in around 5h 11m. Alternatively, FlixBus operates a bus from Frankfurt central train station to Amsterdam Sloterdijk every 2 hours. Tickets cost €35–65 and the journey takes 6h 10m. RegioJet also services this route once daily.

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