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How to get fromFrankfurt am Main to Mendrisioby train, bus, car, or plane

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There are 10 ways to get from Frankfurt am Main to Mendrisio by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Basel

    best
    1. Take the train from Frankfurt to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ic21 / ...
    7h 12m
    CHF 75–597

  2. Fly Frankfurt to Milan Linate Airport, train

    cheapest
    1. Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane plane FRA - LIN
    2. Take the train from Monza to Mendrisiotrain train
    5h 40m
    CHF 43–144

  3. Bus via Basel

    1. Take the bus from Frankfurt, Hauptbahnhof FOB to Basel, Bahnhofbus bus Ivano-Frankivsk
    2. Take the bus from Basel to Comobus bus
    8h 50m

  4. Drive 606 km

    1. Drive from Frankfurt am Main to Mendrisiocar car 606 km
    5h 38m
    CHF 98–141

  5. Fly Frankfurt to Milano Malpensa Airport, train

    1. Fly from Frankfurt (FRA) to Milano Malpensa Airport (MXP)plane plane FRA - MXP
    2. Take the train from Malpensa Aeroporto T1 to Mendrisiotrain train
    4h 44m
    CHF 62–235

  6. Train

    1. Take the train from Frankfurt to Chiassotrain train Ec
    7h 29m
    CHF 205–614

  7. Bus

    1. Take the bus from Frankfurt central train station to Luganobus bus FlixBus N474
    9h 31m
    CHF 55–104

  8. Fly Frankfurt to Zurich Airport, train

    1. Fly from Frankfurt (FRA) to Zurich Airport (ZRH)plane plane FRA - ZRH
    2. Take the train from Zürich HB to Luganotrain train
    5h 4m
    CHF 137–393

  9. Fly Frankfurt to Basel, train

    1. Fly from Frankfurt (FRA) to Basel (BSL)plane plane FRA - BSL
    2. Take the train from Basel SBB to Luganotrain train
    6h 48m
    CHF 125–528

  10. Train to Stuttgart Airport, fly to Milano Malpensa Airport, train

    1. Take the train from Frankfurt to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Milano Malpensa Airport (MXP)plane plane STR - MXP
    3. Take the train from Malpensa Aeroporto T1 to Mendrisiotrain train
    6h 25m
    CHF 99–362

Frankfurt am Main to Mendrisio by train

Calendar76Weekly Trains
Duration7h 12mAverage Duration
TicketCHF 75Cheapest Price
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Questions & Answers

Map of how to get from Frankfurt am Main to Mendrisio.ExpandLaunch map view
  • Distance: 601.4 km
  • Duration: 7h 12m

What companies run services between Frankfurt am Main, Germany and Mendrisio, Switzerland?

You can take a train from Frankfurt to Mendrisio via Basel SBB and Lugano in around 7h 12m. Alternatively, you can take a bus from Frankfurt, Hauptbahnhof FOB to Mendrisio, Autosilo via Basel, Bahnhof SBB, Basel, Brausebad, Basel, Como, Como - Chiesa di San Zenone, and Chiasso, Stazione in around 8h 50m.

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