There are 8 ways to get from Frankfurt am Main to Mussomeli by plane, train, car, car ferry, bus, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Palermo Airport, train
best- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
- Take the train from Palermo Aeroporto to Cammarata-S.G.Geminitrain
7h 42m€128–275Fly Frankfurt to Catania–Fontanarossa Airport, bus
cheapest- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
- Take the bus from Catania Aeroporto Fontanarossa to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
9h 25m€95–232Drive, car ferry
- Drive from Frankfurt am Main to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
- Drive from Port of Palermo to Mussomelicar
30h 10m€238–360Bus, train
- Take the bus from Mühlheim am Main to Catenanuovabus
- Take the train from Catenanuova-Centurip to Caltanissetta C.Letrain Re
- Take the bus from Caltanissetta to Mussomelibus
30h 49mTrain, night train
- Take the train from Frankfurt to Hauptbahnhoftrain 11 / ...
- Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain Nj
- Take the train from Verona Porta Nuova to Roma Terminitrain Fr
- Take the train from Roma Termini to Termini Imeresetrain Ic
- Take the train from Termini Imerese to Cammarata-S.G.Geminitrain Re
33h 14m€270–660Train to Cologne Bonn Airport, fly to Palermo Airport, train
- Take the train from Frankfurt to Siegburg Bftrain
- Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)plane CGN - PMO
- Take the train from Palermo Aeroporto to Cammarata-S.G.Geminitrain
9h 11m€145–514Bus via Rome
- Take the bus from Frankfurt central train station to Roma, Autostazione Tiburtinabus N77
- Take the bus from Roma, Autostazione Tiburtina to Caltanissettabus
- Take the bus from Caltanissetta to Mussomelibus
36h 42m€192–321Bus
- Take the bus from Frankfurt am Main - Stuttgarter Straße to Canicattìbus
- Take the bus from Caltanissetta to Mussomelibus
39h 15m
Frankfurt (FRA) to Palermo Airport (PMO) flights
Questions & Answers
The cheapest way to get from Frankfurt am Main to Mussomeli is to fly and bus which costs €95 - €240 and takes 9h 25m.
The fastest way to get from Frankfurt am Main to Mussomeli is to fly and train which takes 7h 42m and costs €120 - €280.
No, there is no direct bus from Frankfurt am Main station to Mussomeli. However, there are services departing from Frankfurt central train station and arriving at Mussomeli via Roma, Autostazione Tiburtina and Caltanissetta. The journey, including transfers, takes approximately 36h 42m.
No, there is no direct train from Frankfurt am Main to Mussomeli. However, there are services departing from Frankfurt and arriving at Cammarata-S.G.Gemini via Stuttgart Hbf, Verona Porta Nuova, Roma Termini and Termini Imerese. The journey, including transfers, takes approximately 33h 14m.
The distance between Frankfurt am Main and Mussomeli is 1517 km.
The best way to get from Frankfurt am Main to Mussomeli without a car is to bus and train which takes 30h 49m and costs .
It takes approximately 7h 42m to get from Frankfurt am Main to Mussomeli, including transfers.
Frankfurt am Main to Mussomeli bus services, operated by FlixBus, depart from Frankfurt central train station.
Frankfurt am Main to Mussomeli train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Frankfurt am Main to Mussomeli bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
What companies run services between Frankfurt am Main, Germany and Mussomeli, Italy?
You can take a bus from Frankfurt central train station to Mussomeli via Roma, Autostazione Tiburtina, Caltanissetta, and Caltanissetta in around 36h 42m.
- Website
- lufthansa.com
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €95–320
Flights from Frankfurt to Palermo Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €95–330
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €90–310
Flights from Frankfurt to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €65–310
Flights from Cologne Bonn Airport to Palermo Airport via Munich
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Friday, Saturday, Sunday, and Wednesday
- Estimated price
- €95–330
- Website
- ita-airways.com
Flights from Frankfurt to Palermo Airport via Milan Linate
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- €85–190
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €90–310
Flights from Frankfurt to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- €80–160
- Website
- swiss.com
Flights from Frankfurt to Palermo Airport via Zurich
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- €90–310
Flights from Frankfurt to Catania–Fontanarossa Airport via Zurich
- Ave. Duration
- 4h 50m
- When
- Saturday
- Estimated price
- €60–310
Flights from Cologne Bonn Airport to Palermo Airport via Zurich
- Ave. Duration
- 4h 25m
- When
- Sunday
- Estimated price
- €90–320
- Website
- ryanair.com
Flights from Cologne Bonn Airport to Palermo Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- €65–210
- Website
- eurowings.com
Flights from Cologne Bonn Airport to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Tuesday, Thursday, Friday, and Saturday
- Estimated price
- €110–290
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Palermo Aeroporto to Cammarata-S.G.Gemini
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- €15–25
- Website
- Trenitalia
Train from Catenanuova-Centurip to Caltanissetta C.Le
- Ave. Duration
- 1h 19m
- Frequency
- Every 4 hours
- Estimated price
- €9–16
- Website
- Trenitalia
Train from Termini Imerese to Cammarata-S.G.Gemini
- Ave. Duration
- 38 min
- Frequency
- Every 4 hours
- Estimated price
- €6–11
- Website
- Trenitalia
Train from Palermo Aeroporto to Cammarata-S.G.Gemini
- Ave. Duration
- 1h 50m
- Frequency
- 4 times a day
- Estimated price
- €15–25
- Website
- Trenitalia
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Hauptbahnhof
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- €30–150
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- €28–130
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Stuttgart Hbf to Verona Porta Nuova
- Ave. Duration
- 12h 32m
- Frequency
- Twice daily
- Estimated price
- €45–130
- Website
- Nightjet
- Sleeper Carriage
- €100–130
- Couchette Carriage
- €75–90
- Seating Carriage
- €45–60
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Verona Porta Nuova to Roma Termini
- Ave. Duration
- 3h 33m
- Frequency
- Hourly
- Estimated price
- €65–140
- Schedules at
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 11h 5m
- Frequency
- Twice daily
- Estimated price
- €85–190
- Website
- Trenitalia Intercity
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Mühlheim am Main to Catenanuova
- Ave. Duration
- 24h 4m
- Frequency
- Once a week
- Website
- Onebus
Bus from Frankfurt am Main - Stuttgarter Straße to Canicattì
- Ave. Duration
- 35h 26m
- Frequency
- Once a week
- Website
- Onebus
- Phone
- +39 0912742800
- [email protected]
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
Bus from Catania Aeroporto Fontanarossa to Caltanissetta
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- €8–11
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
Bus from Caltanissetta to Mussomeli
- Ave. Duration
- 1h 14m
- Frequency
- Once daily
- Estimated price
- €4–6
- Website
- SAIS Transporti
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Frankfurt central train station to Roma, Autostazione Tiburtina
- Ave. Duration
- 20h 5m
- Frequency
- Once daily
- Estimated price
- €110–190
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Caltanissetta
- Ave. Duration
- 13h 15m
- Frequency
- Twice daily
- Estimated price
- €75–130
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–160
- Website
- Grandi Navi Veloci
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More Questions & Answers
Frankfurt am Main to Mussomeli train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Hauptbahnhof station.
There are 174+ hotels available in Mussomeli.





























