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How to get fromFrankfurt am Main to Prague Main Train Stationby bus, train, night train, car, plane, or subway

Find Transport to Prague Main Train Station

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There are 8 ways to get from Frankfurt am Main to Prague Main Train Station by bus, train, night train, car, plane, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Frankfurt Central Train Station to Prague Wilsonova Bus Stationbus bus : Amsterdam Central Sloterdijk Train Station - Prague Central Bus Station / ...
    6h 15m
    Kč 900–1,700

  2. Bus via Frankfurt am Main

    cheapest
    1. Take the bus from Frankfurt am Main to Prague Florenc Bus Stationbus bus
    8h 58m
    Kč 470–950

  3. Train via Schwandorf

    1. Take the train from Frankfurt to Nürnberg Hbftrain train 41 / ...
    2. Take the train from Nürnberg Hbf to Schwandorftrain train
    3. Take the train from Schwandorf to Praha Hlavni Nadrazitrain train Re
    8h 14m
    Kč 3,238–11,256

  4. Night train

    1. Take the nighttrain from Frankfurt(Main)Sued to Praha Hlavni Nadrazinighttrain night train En
    8h 57m
    Kč 3,300–6,500

  5. Drive 510 km

    1. Drive from Frankfurt am Main to Prague Main Train Stationcar car 510 km
    4h 23m
    Kč 1,868–2,699

  6. Train

    1. Take the train from Frankfurt (Main) Süd to Praha Hlavní nádražítrain train Drf
    10h 4m

  7. Fly to Václav Havel Airport Prague, subway

    1. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    2. Take the subway from Nádraží Veleslavín to Muzeumsubway subway
    4h
    Kč 1,435–3,510

  8. Fly to Dresden Airport, bus

    1. Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane plane FRA - DRS
    2. Take the bus from Dresden to Praha Hlavní nádražíbus bus
    5h 27m

Frankfurt am Main to Prague Main Train Station by bus

Calendar16Weekly Buses
Duration6h 15mAverage Duration
TicketKč 900Cheapest Price
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Questions & Answers

Map of how to get from Frankfurt am Main to Prague Main Train Station.ExpandLaunch map view
  • Distance: 514.2 km
  • Duration: 6h 15m

What companies run services between Frankfurt am Main, Germany and Prague Main Train Station, Czechia?

RegioJet operates a bus from Frankfurt Central Train Station to Prague Wilsonova Bus Station once daily. Tickets cost Kč 900–1,400 and the journey takes 6h 15m. FlixBus also services this route once daily. Alternatively, you can take a train from Frankfurt to Praha Hlavni Nadrazi via Nürnberg Hbf and Schwandorf in around 8h 14m.

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