Rome2Rio

How to get fromFrankfurt am Main to Sienaby plane, train, bus, train (Trenitalia), night train, or car

Find Transport to Siena

See all options

There are 9 ways to get from Frankfurt am Main to Siena by plane, train, bus, train (Trenitalia), night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 14m
    €126–286

  2. Bus

    cheapest
    1. Take the bus from Frankfurt central train station to Florence Villa Constanza Bus Stationbus bus N77 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    18h 28m
    €94–157

  3. Bus via Mühlheim am Main

    1. Take the bus from Mühlheim am Main to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    12h 38m

  4. Train

    1. Take the train from Frankfurt to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    13h
    €148–817

  5. Train, night train

    1. Take the train from Frankfurt to Hauptbahnhoftrain train 11 / ...
    2. Take the nighttrain from Stuttgart Hbf to Verona Porta Nuovanighttrain night train Nj
    3. Take the train from Verona Porta Nuova to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    19h 9m
    €120–353

  6. Fly to Pisa International Airport, train

    1. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    6h 6m
    €120–265

  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 38m
    €118–281

  8. Fly to Venice Marco Polo Airport, train

    1. Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane plane FRA - VCE
    2. Take the train from Venezia Mestre to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 18m
    €110–286

  9. Drive 1,024.9 km

    1. Drive from Frankfurt am Main to Sienacar car 1,024.9 km
    9h 52m
    €159–230

Frankfurt am Main to Siena by train

Calendar76Weekly Trains
Duration13hAverage Duration
Ticket€148Cheapest Price
See schedules

Questions & Answers

Map of how to get from Frankfurt am Main to Siena.ExpandLaunch map view
  • Distance: 834 km
  • Duration: 6h 14m

What companies run services between Frankfurt am Main, Germany and Siena, Italy?

You can take a train from Frankfurt to Siena via Offenbach, Offenbach, Mühlheim, Mühlheim am Main, and Florence Villa Constanza Bus Station in around 12h 38m. Alternatively, you can take a train from Frankfurt to Siena via Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

More Questions & Answers