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How to get fromFrankfurt am Main to Syracuseby plane, bus, train (Trenitalia), train, night train, car, or car ferry

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There are 8 ways to get from Frankfurt am Main to Syracuse by plane, bus, train (Trenitalia), train, night train, car, or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Frankfurt, bus

    best
    1. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane plane FRA - CTA
    2. Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus bus
    6h 3m
    €92–213

  2. Train

    1. Take the train from Frankfurt to Chiassotrain train Ec
    2. Take the train from Chiasso to Milano Centraletrain train S11
    3. Take the train from Milano Centrale to Roma Terminitrain train
    4. Take the train from Roma Termini to Siracusatrain train Ic
    23h 46m
    €398–1,039

  3. Bus

    1. Take the bus from Mühlheim am Main to Catania Central Bus Stationbus bus
    2. Take the bus from Catania Via Archimede to Siracusa - Von Platenbus bus Catania
    27h 29m

  4. Train, night train

    1. Take the train from Frankfurt to Como S. Giovannitrain train Ec
    2. Take the train from Como S. Giovanni to Milano Centraletrain train S11
    3. Take the nighttrain from Milano Centrale to Siracusanighttrain night train Ini
    30h 27m
    €367–969

  5. Train to Stuttgart Airport, fly, bus

    1. Take the train from Frankfurt to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane plane STR - CTA
    3. Take the bus from Catania Airport to Siracusa - v.le Scala Grecabus bus
    7h 29m
    €112–383

  6. Train via Basel

    1. Take the train from Frankfurt to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Roma Terminitrain train
    5. Take the train from Roma Termini to Siracusatrain train Ic
    24h 23m
    €268–1,037

  7. Bus via Foggia

    1. Take the bus from Frankfurt central train station to Foggiabus bus N422
    2. Take the bus from Foggia to Siracusabus bus 590
    35h 40m
    €188–309

  8. Drive, car ferry

    1. Drive from Frankfurt am Main to Villa S. Giovannicar car
    2. Take the carferry from Villa S. Giovanni to Tresmestiericarferry car ferry
    3. Drive from Tresmestieri to Syracusecar car
    19h 46m
    €336–495

Frankfurt am Main to Syracuse by train and night train

Calendar6Weekly Services
Duration30h 27mAverage Duration
Ticket€367Cheapest Price
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Questions & Answers

Map of how to get from Frankfurt am Main to Syracuse.ExpandLaunch map view
  • Distance: 1,562.8 km
  • Duration: 6h 3m

What companies run services between Frankfurt am Main, Germany and Syracuse, Italy?

You can take a train from Frankfurt to Siracusa via Chiasso, Milano Centrale, and Roma Termini in around 23h 46m. Alternatively, you can take a train from Frankfurt to Siracusa - Von Platen via Offenbach, Offenbach, Mühlheim, Mühlheim am Main, Catania Central Bus Station, and Catania Via Archimede in around 27h 29m.

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