Rome2Rio

How to get fromFrederick to Charleston Amtrak Stationby bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Find Transport to Charleston Amtrak Station

See all options

There are 9 ways to get from Frederick to Charleston Amtrak Station by bus, plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Charleston International Airport

    best
    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Charleston International Airport (CHS)plane plane BWI - CHS
    5h 22m
    $463–1,290

  2. Bus

    cheapest
    1. Take the bus from Frederick Bus Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Charleston Bus Stationbus bus
    15h 40m
    $97–198

  3. Train

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train Marc
    2. Take the train from Washington Union Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    12h 4m
    $162–352

  4. Drive 535.2 mi

    1. Drive from Frederick to Charleston Amtrak Stationcar car 535.2 mi
    9h 58m
    $98–142

  5. Train to Ronald Reagan Washington National Airport, fly to Charleston International Airport

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Charleston International Airport (CHS)plane plane DCA - CHS
    6h 18m
    $441–1,121

  6. Bus to Washington Dulles International Airport, fly to Charleston International Airport

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Charleston International Airport (CHS)plane plane IAD - CHS
    6h 36m
    $558–1,129

  7. Bus to Baltimore-Washington International Airport, fly to Myrtle Beach, bus

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane plane BWI - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    6h 51m
    $335–780

  8. Train to Ronald Reagan Washington National Airport, fly to Myrtle Beach, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Myrtle Beach (MYR)plane plane DCA - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    7h 59m
    $108–530

  9. Bus to Washington Dulles International Airport, fly to Savannah, train

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Savannah (SAV)plane plane IAD - SAV
    3. Take the train from Savannah Station to Charleston Amtrak Stationtrain train
    7h 47m
    $159–615

Frederick to Charleston Amtrak Station by train

Calendar14Weekly Trains
Duration12h 4mAverage Duration
Ticket$162Cheapest Price
See schedules

Questions & Answers

Map of how to get from Frederick to Charleston Amtrak Station.ExpandLaunch map view
  • Distance: 527.7 mi
  • Duration: 5h 22m

What companies run services between Frederick, MD, USA and Charleston Amtrak Station, SC, USA?

You can take a train from FREDERICK MARC eb to Charleston Amtrak Station via Washington Union Station in around 12h 4m. Alternatively, you can take a bus from Frederick Bus Station to Charleston Bus Station via Washington Union Station and Raleigh Bus Station in around 15h 40m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers