There are 7 ways to get from Frederick to Darlington by bus (Greyhound, Flixbus), train (Amtrak), car, bus, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Frederick Bus Station to Washington Union Stationbus Greyhound US0164 / ...
- Take the bus from Washington Union Station to Florencebus FlixBus N2472
10h 19m$94–159Drive 442.3 mi
cheapest- Drive from Frederick to Darlingtoncar 442.3 mi
7h 40m$81–117Train
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain Marc
- Take the train from Washington Union Station to Florence Stationtrain Palmetto / ...
10h 44m$167–327Bus to Baltimore-Washington International Airport, fly, bus
- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane BWI - MYR
- Take the bus from Myrtle Beach to Florencebus
6h 53mTrain, bus
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain
- Take the bus from Washington Union Station to Richmond Main Street Amtrak Stationbus
- Take the bus from Richmond - Brook + Walmart Nhood Mkt to Florence, SCbus Nyc
13h 10m$100–146Train to Ronald Reagan Washington National Airport, fly, bus
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Myrtle Beach (MYR)plane DCA - MYR
- Take the bus from Myrtle Beach to Florencebus
7h 36mBus to Washington Dulles International Airport, fly, bus
- Take the bus from Frederick Transit Station to Market St & Harrison Stbus
- Fly from Washington Dulles International Airport (IAD) to Myrtle Beach (MYR)plane IAD - MYR
- Take the bus from Myrtle Beach to Florencebus
9h 35m
Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Frederick to Darlington is to drive which costs $80 - $120 and takes 7h 40m.
The fastest way to get from Frederick to Darlington is to drive which takes 7h 40m and costs $80 - $120.
No, there is no direct bus from Frederick station to Darlington. However, there are services departing from Frederick Bus Station and arriving at Florence via Washington Union Station. The journey, including transfers, takes approximately 10h 19m.
No, there is no direct train from Frederick to Darlington station. However, there are services departing from FREDERICK MARC eb and arriving at Florence Station via Washington Union Station. The journey, including transfers, takes approximately 10h 44m.
The distance between Frederick and Darlington is 464 miles. The road distance is 444.9 miles.
The best way to get from Frederick to Darlington without a car is to bus which takes 10h 19m and costs $90 - $160.
It takes approximately 10h 19m to get from Frederick to Darlington, including transfers.
Frederick to Darlington bus services, operated by Greyhound-us, depart from Frederick Bus Station.
Frederick to Darlington train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.
The best way to get from Frederick to Darlington is to bus which takes 10h 19m and costs $90 - $160. Alternatively, you can train, which costs $160 - $330 and takes 10h 44m.
What companies run services between Frederick, MD, USA and Darlington, SC, USA?
You can take a bus from Frederick Bus Station to Darlington via Washington Union Station and Florence in around 10h 19m. Alternatively, you can take a train from FREDERICK MARC eb to Darlington via Washington Union Station and Florence Station in around 10h 44m.
- Website
- aa.com
Flights from Baltimore-Washington International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 31m
- When
- Monday, Tuesday, Wednesday, Friday, and Sunday
- Estimated price
- $65–350
Flights from Ronald Reagan Washington National Airport to Myrtle Beach
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $75–470
Flights from Ronald Reagan Washington National Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $90–500
Flights from Washington Dulles International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $50–300
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Myrtle Beach
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $55–330
- Phone
- 1-866-743-3682
- Website
- mta.maryland.gov
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–12
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–12
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–10
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Washington Union Station to Florence Station
- Ave. Duration
- 7h 48m
- Frequency
- Twice daily
- Estimated price
- $130–270
- Website
- https://www.amtrak.com/home.html
- Website
- greyhound.com
Bus from Frederick Bus Station to Washington Union Station
- Ave. Duration
- 1h 10m
- Frequency
- 3 times a day
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Frederick Bus Station to Washington Union Station
- Ave. Duration
- 1h 10m
- Frequency
- 3 times a day
- Estimated price
- $6–13
- Website
- https://www.greyhound.com/
- Website
- flixbus.com
Bus from Washington Union Station to Florence
- Ave. Duration
- 8h
- Frequency
- Once daily
- Schedules at
- flixbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Washington Union Station to Florence
- Ave. Duration
- 8h
- Frequency
- 5 times a week
- Estimated price
- $65–120
- Schedules at
- flixbus.com
- Website
- example.com
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Schedules at
- example.com
- Website
- example.com
Bus from Myrtle Beach to Florence
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Schedules at
- example.com
Bus from Myrtle Beach to Florence
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Schedules at
- example.com
Bus from Myrtle Beach to Florence
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Schedules at
- example.com
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Washington Union Station to Richmond Main Street Amtrak Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-800-827-3490
- [email protected]
- Website
- virginiabreeze.drpt.virginia.gov
Bus from Washington Union Station to Richmond Main Street Amtrak Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $24–30
- Schedules at
- virginiabreeze.drpt.virginia.gov
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from Richmond - Brook + Walmart Nhood Mkt to Florence, SC
- Ave. Duration
- 5h 53m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $50–75
- Phone
- +1 703-771-5665
- Website
- loudoun.gov
Bus from Frederick Transit Station to Market St & Harrison St
- Ave. Duration
- 58 min
- Frequency
- Once daily
- Estimated price
- $1–11
- Schedules at
- loudoun.gov
- Local & Metro
- $1–2
- Commuter
- $11
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More Questions & Answers
Frederick to Darlington bus services, operated by Greyhound-us, arrive at Washington Union Station.
Frederick to Darlington train services, operated by Maryland Transit, arrive at Washington Union Station.
Yes, the driving distance between Frederick to Darlington is 445 miles. It takes approximately 7h 40m to drive from Frederick to Darlington.
Book your Frederick to Darlington bus tickets online with Omio.
There are 53+ hotels available in Darlington.









