What is the cheapest way to get from Frederick to Florence?

The cheapest way to get from Frederick to Florence is to drive which costs $80 - $120 and takes 7h 31m.

What is the fastest way to get from Frederick to Florence?

The fastest way to get from Frederick to Florence is to bus and fly which takes 6h 12m and costs $350 - $850.

Is there a direct bus between Frederick and Florence?

No, there is no direct bus from Frederick station to Florence station. However, there are services departing from Frederick Bus Station and arriving at Florence Bus Station via Washington Union Station and Raleigh Bus Station. The journey, including transfers, takes approximately 10h 19m.

Is there a direct train between Frederick and Florence?

No, there is no direct train from Frederick to Florence station. However, there are services departing from FREDERICK MARC eb and arriving at Florence Station via Washington Union Station. The journey, including transfers, takes approximately 10h 28m.

How far is it from Frederick to Florence?

The distance between Frederick and Florence is 458 miles. The road distance is 441 miles.

How do I travel from Frederick to Florence without a car?

The best way to get from Frederick to Florence without a car is to bus which takes 10h 19m and costs $85 - $160.

How long does it take to get from Frederick to Florence?

It takes approximately 10h 19m to get from Frederick to Florence, including transfers.

Where do I catch the Frederick to Florence bus from?

Frederick to Florence bus services, operated by Greyhound USA, depart from Frederick Bus Station.

Where do I catch the Frederick to Florence train from?

Frederick to Florence train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.

Train or bus from Frederick to Florence?

The best way to get from Frederick to Florence is to bus which takes 10h 19m and costs $85 - $160. Alternatively, you can train, which costs $130 - $290 and takes 10h 28m.

Where does the Frederick to Florence bus arrive?

Frederick to Florence bus services, operated by Greyhound USA, arrive at Washington Union Station.

Where does the Frederick to Florence train arrive?

Frederick to Florence train services, operated by Maryland Transit, arrive at Washington Union Station.

Can I drive from Frederick to Florence?

Yes, the driving distance between Frederick to Florence is 441 miles. It takes approximately 7h 31m to drive from Frederick to Florence.

How do I get a bus ticket from Frederick to Florence?

Book your Frederick to Florence bus tickets online with Omio and FlixBus.

Where can I stay near Florence?

There are 48+ hotels available in Florence.

Frederick to Florence - 7 ways to travel via train, bus, car, and plane

How to get fromFrederick to Florence

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There are 7 ways to get from Frederick to Florence by bus (Greyhound, Flixbus), train (Amtrak), car, bus, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from Frederick Bus Station to Washington Union Stationbus
2. Take the bus from Washington Union Station to Raleigh Bus Stationbus
3. Take the bus from Raleigh Bus Station to Florence Bus Stationbus
10h 19m
$85–155
Drive 438.5 mi
cheapest
1. Drive from Frederick to Florencecar 438.5 mi
7h 31m
$80–116
Train
1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain Marc
2. Take the train from Washington Union Station to Florence Stationtrain Palmetto / ...
10h 28m
$132–282
Bus to Baltimore-Washington International Airport, fly, bus
1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
2. Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane BWI - MYR
3. Take the bus from Myrtle Beach to Florencebus
6h 12m
$359–804
Train, bus
1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain
2. Take the bus from Washington Union Station to Fayetteville Bus Stationbus
3. Take the train from Fayetteville Amtrak Station to Florence Stationtrain
11h 46m
$103–177
Train to Ronald Reagan Washington National Airport, fly, bus
1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
2. Fly from Ronald Reagan Washington National Airport (DCA) to Myrtle Beach (MYR)plane DCA - MYR
3. Take the bus from Myrtle Beach to Florencebus
7h 21m
$132–555
Bus to Washington Dulles International Airport, fly, bus
1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus
2. Fly from Washington Dulles International Airport (IAD) to Myrtle Beach (MYR)plane IAD - MYR
3. Take the bus from Myrtle Beach to Florencebus
9h 20m
$404–1,493

Frederick to Florence by bus

22Weekly Buses

10h 19mAverage Duration

$85Cheapest Price

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Questions & Answers

Map of how to get from Frederick to Florence.

Launch map view

Distance: 455 mi
Duration: 10h 19m

What companies run services between Frederick, MD, USA and Florence, SC, USA?

You can take a bus from Frederick Bus Station to Florence Bus Station via Washington Union Station and Raleigh Bus Station in around 10h 19m. Alternatively, you can take a train from FREDERICK MARC eb to Florence Station via Washington Union Station in around 10h 28m.

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