There are 8 ways to get from Frederick to Hyannis by train, plane, bus, bus (Greyhound, Flixbus), car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Ronald Reagan Washington National Airport, fly to Barnstable Municipal Airport
best- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Barnstable Municipal Airport (HYA)plane DCA - HYA
6h 10m$116–717Drive 475.5 mi
cheapest- Drive from Frederick to Hyanniscar 475.5 mi
9h 13m$87–126Bus, train
- Take the bus from Frederick Transit Center to BWI Amtrak Stationbus
- Take the train from BWI Thurgood Marshall to Bostontrain
- Take the bus from Boston to Hyannisbus
11h 21m$182–379Bus
- Take the bus from Frederick Bus Station to Baltimore Downtown Bus Terminal, Baltimore, MDbus
- Take the bus from Baltimore Downtown Bus Station to Bostonbus
- Take the bus from Boston South Buses to Hyannis Transportation Centerbus
12h 57m$100–157Bus to Baltimore-Washington International Airport, fly to Boston Logan Airport, bus
- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Boston Logan Airport (BOS)plane BWI - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
6h 41m$245–1,094Train, subway to Washington Dulles International Airport, fly to Boston Logan Airport, bus
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Boston Logan Airport (BOS)plane IAD - BOS
- Take the bus from Logan International Airport to Hyannis Transportation Centerbus
8h 1m$534–1,156Train, bus
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain
- Take the train from Washington Union Station to Bostontrain
- Take the bus from Boston South Buses to Hyannis Transportation Centerbus
11h 58m$139–317Bus via New York
- Take the bus from Frederick Bayrunner Office to Baltimore Downtown Bus Terminal, Baltimore, MDbus
- Take the bus from Baltimore to New Yorkbus
- Take the bus from New York to Providencebus
- Take the bus from Providence to Hyannisbus
13h 17m$163–282
Frederick to Hyannis by bus, train, and foot
Comparing Your Travel Options
The cheapest way to get from Frederick to Hyannis is to drive which costs $85 - $130 and takes 9h 13m.
The fastest way to get from Frederick to Hyannis is to train and fly which takes 6h 10m and costs $110 - $750.
No, there is no direct bus from Frederick station to Hyannis. However, there are services departing from Frederick Bus Station and arriving at Hyannis Transportation Center via Baltimore Downtown Bus Station and Boston South Buses. The journey, including transfers, takes approximately 12h 57m.
The distance between Frederick and Hyannis is 469 miles. The road distance is 478.3 miles.
The best way to get from Frederick to Hyannis without a car is to bus and train which takes 11h 21m and costs $180 - $380.
It takes approximately 6h 10m to get from Frederick to Hyannis, including transfers.
Frederick to Hyannis bus services, operated by BayRunner Shuttle, depart from Frederick Bus Station.
Frederick to Hyannis bus services, operated by BayRunner Shuttle, arrive at Baltimore Downtown Bus Terminal, Baltimore, MD station.
Yes, the driving distance between Frederick to Hyannis is 478 miles. It takes approximately 9h 13m to drive from Frederick to Hyannis.
Book your Frederick to Hyannis bus tickets online with Omio.
What companies run services between Frederick, MD, USA and Hyannis, MA, USA?
You can take a bus from Frederick Bus Station to Hyannis Transportation Center via Baltimore Downtown Bus Station, Boston, and Boston South Buses in around 12h 57m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Boston Logan Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $60–400
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Frederick Transit Center to BWI Amtrak Station
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Estimated price
- $10–16
- Website
- Amtrak
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Booking & Getting There
There are 843+ hotels available in Hyannis.








