There are 10 ways to get from Frederick to Ithaca by bus, train, car, subway, plane, bus (Greyhound), or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train
best- Take the bus from Frederick Transit Center to BWI Amtrak Stationbus
- Take the train from BWI Thurgood Marshall to Newark Penn Stationtrain
- Take the bus from Newark Penn Station to Ithacabus
9h 55m$138–854Drive 256 mi
cheapest- Drive from Frederick to Ithacacar 256 mi
5h 45m$47–68Train, subway to Washington Dulles International Airport, fly to Ithaca Tompkins Regional Airport
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Ithaca Tompkins Regional Airport (ITH)plane IAD - ITH
6h 11m$51–326Bus via Scranton
- Take the bus from Frederick Bus Station to Baltimore Downtown Bus Terminal, Baltimore, MDbus
- Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus
- Take the bus from Harrisburg, Pa to Scranton, Pabus 770
- Take the bus from Scranton, Pa to Ithacabus 246
11h 35m$66–171Bus
- Take the bus from Frederick Bus Station to Washington Union Stationbus Greyhound US0164 / ...
- Take the bus from Washington Union Station to Ithacabus FlixBus 2682
11h 55m$82–131Bus to Baltimore-Washington International Airport, fly to Rochester, bus
- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Rochester (ROC)plane BWI - ROC
- Take the bus from Rochester to Ithacabus
6h 34m$216–883Train, subway to Washington Dulles International Airport, fly to Rochester, bus
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Rochester (ROC)plane IAD - ROC
- Take the bus from Rochester to Ithacabus
7h 47m$135–745Train to Ronald Reagan Washington National Airport, fly to Syracuse Hancock International Airport, bus
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Syracuse Hancock International Airport (SYR)plane DCA - SYR
- Take the bus from Syracuse Bus Station to Ithacabus
7h 30m$168–1,158Train, subway to Washington Dulles International Airport, fly to Wilkes-Barre/Scranton International Airport, bus
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Wilkes-Barre/Scranton International Airport (AVP)plane IAD - AVP
- Take the bus from Scranton, Pa to Ithacabus
8h 15m$113–481Train, subway to Washington Dulles International Airport, fly to Syracuse Hancock International Airport, bus
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Syracuse Hancock International Airport (SYR)plane IAD - SYR
- Take the bus from Syracuse Bus Station to Ithacabus
8h 10m$113–707
Frederick to Ithaca by bus and train
Comparing Your Travel Options
The cheapest way to get from Frederick to Ithaca is to drive which costs $45 - $70 and takes 5h 45m.
The fastest way to get from Frederick to Ithaca is to drive which takes 5h 45m and costs $45 - $70.
No, there is no direct bus from Frederick station to Ithaca. However, there are services departing from Frederick Bus Station and arriving at Ithaca via Baltimore Downtown Bus Station, Harrisburg, Pa and Scranton, Pa. The journey, including transfers, takes approximately 11h 35m.
The distance between Frederick and Ithaca is 449 miles. The road distance is 257.5 miles.
The best way to get from Frederick to Ithaca without a car is to bus and train which takes 9h 55m and costs $130 - $900.
It takes approximately 9h 55m to get from Frederick to Ithaca, including transfers.
Frederick to Ithaca bus services, operated by BayRunner Shuttle, depart from Frederick Bus Station.
Frederick to Ithaca bus services, operated by BayRunner Shuttle, arrive at Baltimore Downtown Bus Terminal, Baltimore, MD station.
Yes, the driving distance between Frederick to Ithaca is 257 miles. It takes approximately 5h 45m to drive from Frederick to Ithaca.
Book your Frederick to Ithaca bus tickets online with Omio.
What companies run services between Frederick, MD, USA and Ithaca, NY, USA?
You can take a bus from Frederick Bus Station to Ithaca via Baltimore Downtown Bus Station, Harrisburg, Pa, and Scranton, Pa in around 11h 35m.
- Website
- united.com
Flights from Washington Dulles International Airport to Ithaca Tompkins Regional Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $45–310
Flights from Washington Dulles International Airport to Rochester
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $90–650
Flights from Washington Dulles International Airport to Wilkes-Barre/Scranton International Airport
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $45–350
Flights from Washington Dulles International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $95–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from BWI Thurgood Marshall to Newark Penn Station
- Ave. Duration
- 3h 14m
- Frequency
- Hourly
- Estimated price
- $45–110
- Website
- Amtrak
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Frederick Transit Center to BWI Amtrak Station
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Estimated price
- $10–16
- Website
- Amtrak
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are 85+ hotels available in Ithaca.





