There are 11 ways to get from Frederick to Key Largo by bus, plane, shuttle, bus (Greyhound, Flixbus), train, car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly to Miami International Airport, shuttle
best- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Miami International Airport (MIA)plane BWI - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 15m$242–624Bus
cheapest- Take the bus from Frederick Bus Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
25h 55m$176–276Train, bus
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain
- Take the train from Washington Union Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
29h 4m$294–733Drive 1,149.9 mi
- Drive from Frederick to Key Largocar 1,149.9 mi
19h 12m$210–304Train to Ronald Reagan Washington National Airport, fly to Miami International Airport, shuttle
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Miami International Airport (MIA)plane DCA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 41m$266–1,147Bus to Baltimore-Washington International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Fort Lauderdale–Hollywood International Airport (FLL)plane BWI - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
7h 40m$327–1,354Train to Ronald Reagan Washington National Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Fort Lauderdale–Hollywood International Airport (FLL)plane DCA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
8h 9m$776–1,767Train, subway to Washington Dulles International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Fort Lauderdale–Hollywood International Airport (FLL)plane IAD - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
8h 55m$256–616Train, subway to Washington Dulles International Airport, fly to Miami International Airport, shuttle
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Miami International Airport (MIA)plane IAD - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
8h 37m$236–696Bus to Baltimore-Washington International Airport, fly to President Donald J. Trump International Airport, train, bus
- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to President Donald J. Trump International Airport (PBI)plane BWI - PBI
- Take the train from West Palm Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
10h 45m$193–682Train, bus via Rockville
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the train from Rockville Amtrak to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
34h 50m$324–781
Frederick to Key Largo by bus
Comparing Your Travel Options
The cheapest way to get from Frederick to Key Largo is to bus which costs $170 - $280 and takes 25h 55m.
The fastest way to get from Frederick to Key Largo is to bus and fly and shuttle which takes 7h 15m and costs $240 - $650.
No, there is no direct bus from Frederick station to Key Largo. However, there are services departing from Frederick Bus Station and arriving at Key Largo Bus Stop via Washington Union Station and Miami Airport Station. The journey, including transfers, takes approximately 25h 55m.
The distance between Frederick and Key Largo is 1071 miles. The road distance is 1156.6 miles.
The best way to get from Frederick to Key Largo without a car is to bus which takes 25h 55m and costs $170 - $280.
It takes approximately 7h 15m to get from Frederick to Key Largo, including transfers.
Frederick to Key Largo bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Frederick to Key Largo bus services, operated by Greyhound USA, arrive at Washington Union Station.
Yes, the driving distance between Frederick to Key Largo is 1157 miles. It takes approximately 19h 12m to drive from Frederick to Key Largo.
Book your Frederick to Key Largo bus tickets online with Omio and FlixBus.
What companies run services between Frederick, MD, USA and Key Largo, FL, USA?
You can take a bus from Frederick Bus Station to Key Largo Bus Stop via Washington Union Station and Miami Airport Station in around 25h 55m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Miami International Airport
- Ave. Duration
- 2h 38m
- When
- Every day
- Estimated price
- $100–550
Flights from Baltimore-Washington International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $110–600
Flights from Baltimore-Washington International Airport to Fort Lauderdale–Hollywood International Airport via Raleigh/Durham
- Ave. Duration
- 5h 5m
- When
- Sunday
- Estimated price
- $110–600
Flights from Ronald Reagan Washington National Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 38m
- When
- Every day
- Estimated price
- $140–750
Flights from Baltimore-Washington International Airport to President Donald J. Trump International Airport
- Ave. Duration
- 2h 31m
- When
- Every day
- Estimated price
- $100–550
Flights from Baltimore-Washington International Airport to President Donald J. Trump International Airport via Orlando
- Ave. Duration
- 4h 22m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
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Booking & Getting There
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