There are 4 ways to get from Frederick to Lancaster by bus (Greyhound), bus, train, car, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, line 18 bus
best- Take the bus from Frederick to Baltimorebus
- Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus
- Take the bus from AMTRAK ETown to W. Chestnut & Water St.bus 18
6h 46mDrive 81.4 mi
cheapest- Drive from Frederick to Lancastercar 81.4 mi
2h 10m$15–22Bus, train (Amtrak)
- Take the bus from Frederick Transit Center to BWI Amtrak Stationbus
- Take the train from BWI Thurgood Marshall to 30th Street Stationtrain
- Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain
7h 25mTrain
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain
- Take the train from Washington Union Station to 30th Street Stationtrain
- Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain
8h 11m$117–207
Comparing Your Travel Options
The cheapest way to get from Frederick to Lancaster is to drive which costs $14 - $22 and takes 2h 10m.
The fastest way to get from Frederick to Lancaster is to drive which takes 2h 10m and costs $14 - $22.
No, there is no direct bus from Frederick to Lancaster. However, there are services departing from Frederick and arriving at W. Chestnut & Water St. via Baltimore Downtown Bus Station and AMTRAK ETown. The journey, including transfers, takes approximately 6h 46m.
No, there is no direct train from Frederick to Lancaster station. However, there are services departing from FREDERICK MARC eb and arriving at Elizabethtown Amtrak Station via Washington Union Station and 30th Street Station. The journey, including transfers, takes approximately 8h 11m.
The distance between Frederick and Lancaster is 165 miles. The road distance is 81.9 miles.
The best way to get from Frederick to Lancaster without a car is to bus and line 18 bus which takes 6h 46m and costs .
It takes approximately 6h 46m to get from Frederick to Lancaster, including transfers.
Frederick to Lancaster bus services, operated by BayRunner Shuttle, depart from Frederick station.
Frederick to Lancaster train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.
The best way to get from Frederick to Lancaster is to bus and line 18 bus which takes 6h 46m and costs . Alternatively, you can train, which costs $110 - $210 and takes 8h 11m.
What companies run services between Frederick, MD, USA and Lancaster, PA, USA?
You can take a bus from Frederick to W. Chestnut & Water St. via Baltimore Downtown Bus Station, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 6h 46m. Alternatively, you can take a train from FREDERICK MARC eb to W. Chestnut & Mary St. via Washington Union Station, 30th Street Station, Elizabethtown Amtrak Station, and AMTRAK ETown in around 8h 11m.
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from BWI Thurgood Marshall to 30th Street Station
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from 30th Street Station to Elizabethtown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Washington Union Station to 30th Street Station
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- $70–120
- Website
- Amtrak
Train from 30th Street Station to Elizabethtown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $45–75
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from BWI Thurgood Marshall to 30th Street Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from Washington Union Station to 30th Street Station
- Ave. Duration
- 1h 42m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 50 min
- Frequency
- 3 times a day
- Estimated price
- $65–110
- Schedules at
- BayRunner Shuttle
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Baltimore Downtown Bus Station to Harrisburg Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a week
- Estimated price
- $13–21
- Website
- Greyhound
- Phone
- +1 717-397-4246
- Website
- Red Rose Transit
Bus from AMTRAK ETown to W. Chestnut & Water St.
- Ave. Duration
- 56 min
- Frequency
- Every 4 hours
- Website
- Red Rose Transit
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Frederick Transit Center to BWI Amtrak Station
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Website
- Amtrak
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Frederick to Lancaster bus services, operated by BayRunner Shuttle, arrive at Baltimore station.
Frederick to Lancaster train services, operated by Maryland Transit, arrive at Washington Union Station.
Yes, the driving distance between Frederick to Lancaster is 82 miles. It takes approximately 2h 10m to drive from Frederick to Lancaster.
There are 208+ hotels available in Lancaster.















