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How to get fromFrederick to Louisvilleby bus, plane, bus (Greyhound), train, car, subway, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Frederick to Louisville by bus, plane, bus (Greyhound), train, car, subway, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Louisville International Airport

    best
    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    5h 21m
    $188–807

  2. Bus via Columbus

    cheapest
    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbusbus bus
    3. Take the bus from Columbus to Louisvillebus bus
    14h 20m
    $80–156

  3. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    23h 46m
    $194–477

  4. Drive  546.3 mi

    1. Drive from Frederick to Louisvillecar car 546.3 mi
    9h 40m
    $100–144

  5. Train to Ronald Reagan Washington National Airport, fly to Louisville International Airport

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    5h 56m
    $157–970

  6. Train to Ronald Reagan Washington National Airport, fly to Blue Grass Airport, drive

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Blue Grass Airport (LEX)plane plane DCA - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 47m
    $104–586

  7. Train, subway to Washington Dulles International Airport, fly to Louisville International Airport

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Louisville International Airport (SDF)plane plane IAD - SDF
    6h 23m
    $102–619

  8. Bus to Baltimore-Washington International Airport, fly to Covington, bus

    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Covington (CVG)plane plane BWI - CVG
    3. Take the bus from Cincinnati to Louisvillebus bus
    7h 43m
    $208–1,001

  9. Bus

    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Cincinnatibus bus
    3. Take the bus from Cincinnati to Louisvillebus bus
    14h 55m
    $85–164

Frederick to Louisville by bus

Calendar14Weekly Buses
Duration14h 20mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

Map of how to get from Frederick to Louisville.ExpandLaunch map view
  • Distance: 559.6 mi
  • Duration: 5h 21m

What companies run services between Frederick, MD, USA and Louisville, KY, USA?

You can take a bus from Frederick Bus Station to Louisville via Pittsburgh Intermodal Station and Columbus in around 14h 20m.

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