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How to get fromFrederick to Louisvilleby bus, plane, bus (Greyhound), train, car, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Frederick to Louisville by bus, plane, bus (Greyhound), train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Louisville International Airport

    best
    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    4h 51m
    $165–640

  2. Bus via Columbus

    cheapest
    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Wilson & Ferrell Shell Station - Columbusbus bus
    3. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus bus
    14h 25m
    $78–169

  3. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    24h 21m
    $254–527

  4. Drive 546.3 mi

    1. Drive from Frederick to Louisvillecar car 546.3 mi
    9h 39m
    $100–144

  5. Train to Ronald Reagan Washington National Airport, fly to Louisville International Airport

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    5h 55m
    $138–820

  6. Bus to Washington Dulles International Airport, fly to Louisville International Airport

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Louisville International Airport (SDF)plane plane IAD - SDF
    6h
    $85–488

  7. Train to Ronald Reagan Washington National Airport, fly to Blue Grass Airport, drive

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Blue Grass Airport (LEX)plane plane DCA - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 46m
    $210–1,236

  8. Bus

    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Cincinnatibus bus
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    15h 2m
    $84–182

Frederick to Louisville by bus

Calendar14Weekly Buses
Duration14h 25mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

Map of how to get from Frederick to Louisville.ExpandLaunch map view
  • Distance: 548.3 mi
  • Duration: 4h 51m

What companies run services between Frederick, MD, USA and Louisville, KY, USA?

You can take a bus from Frederick Bus Station to Louisville, KY Bus Station via Pittsburgh Intermodal Station and N Wilson Rd & Ferrell Pl - Columbus in around 14h 25m.

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