Rome2Rio

How to get fromFrederick to Niagara Fallsby bus, plane, bus (Greyhound), train (Amtrak), car, train, or subway

Find Transport to Niagara Falls

See all options

There are 13 ways to get from Frederick to Niagara Falls by bus, plane, bus (Greyhound), train (Amtrak), car, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport, bus

    best
    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    5h 25m
    $156–661

  2. Drive  326.3 mi

    cheapest
    1. Drive from Frederick to Niagara Fallscar car 326.3 mi
    7h 32m
    $60–86

  3. Bus (Greyhound)

    1. Take the bus from Frederick Bus Station to Cleveland Bus Stationbus bus Greyhound US0164
    2. Take the bus from Cleveland Bus Station to Buffalobus bus Greyhound US0171 / ...
    13h 33m
    $83–131

  4. Train

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Stationtrain train
    15h 6m
    $167–412

  5. Train to Ronald Reagan Washington National Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Buffalo Niagara International Airport (BUF)plane plane DCA - BUF
    3. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    6h 2m
    $110–774

  6. Train, subway to Washington Dulles International Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Buffalo Niagara International Airport (BUF)plane plane IAD - BUF
    4. Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus bus
    6h 29m
    $75–483

  7. Bus to Baltimore-Washington International Airport, fly to Rochester, train

    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Rochester (ROC)plane plane BWI - ROC
    3. Take the train from Rochester to Niagara Falls Amtrak Stationtrain train
    6h 51m
    $219–996

  8. Train, subway to Washington Dulles International Airport, fly to Rochester

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Rochester (ROC)plane plane IAD - ROC
    4. Take the train from Rochester to Niagara Falls Amtrak Stationtrain train
    8h 3m
    $138–858

  9. Train, subway to Washington Dulles International Airport, fly to Toronto Pearson International Airport, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Toronto Pearson International Airport (YYZ)plane plane IAD - YYZ
    4. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    8h 28m
    $570–1,181

  10. Train, subway to Washington Dulles International Airport, fly to Toronto Island Airport, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Toronto Island Airport (YTZ)plane plane IAD - YTZ
    4. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    8h 18m
    $134–572

  11. Bus via Pittsburgh

    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    14h 28m
    $77–238

  12. Bus, train

    1. Take the bus from Frederick Transit Center to BWI Amtrak Stationbus bus
    2. Take the train from BWI Thurgood Marshall to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Stationtrain train
    15h 8m
    $223–1,074

  13. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the bus from Washington Union Station to Ithacabus bus
    3. Take the bus from Ithaca to Niagara Falls USAbus bus
    18h 5m
    $104–177

Frederick to Niagara Falls by bus (Greyhound)

Calendar7Weekly Buses
Duration13h 33mAverage Duration
Ticket$83Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Frederick to Niagara Falls.ExpandLaunch map view
  • Distance: 371.6 mi
  • Duration: 5h 25m

What companies run services between Frederick, MD, USA and Niagara Falls, NY, USA?

You can take a bus from Frederick Bus Station to Main Street & Pine Avenue via Cleveland Bus Station, Buffalo, and Ellicott Street & MTC Static in around 13h 33m. Alternatively, you can take a train from FREDERICK MARC eb to Niagara Falls Amtrak Station via Washington Union Station and Ny Moynihan Train Hall At Penn Station in around 15h 6m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Booking & Getting There