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How to get fromFrederick to Niagara Fallsby bus, plane, bus (Greyhound), train (Amtrak), car, or train

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There are 13 ways to get from Frederick to Niagara Falls by bus, plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport, line 40 bus

    best
    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    3. Take the bus from Ellicott Street & MTC Static to Main Street & Pine Avenuebus bus
    5h 48m
    $147–659

  2. Drive  326.3 mi

    cheapest
    1. Drive from Frederick to Niagara Fallscar car 326.3 mi
    7h 31m
    $60–86

  3. Bus (Greyhound)

    1. Take the bus from Frederick Bus Station to Cleveland Bus Stationbus bus Greyhound US0164
    2. Take the bus from Cleveland Bus Station to Buffalobus bus Greyhound US0171 / ...
    13h 33m
    $76–143

  4. Train

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Stationtrain train
    15h 6m
    $182–432

  5. Train to Ronald Reagan Washington National Airport, fly to Buffalo Niagara International Airport, line 40 bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Buffalo Niagara International Airport (BUF)plane plane DCA - BUF
    3. Take the bus from Ellicott Street & MTC Static to Main Street & Pine Avenuebus bus
    6h 55m
    $110–772

  6. Bus to Washington Dulles International Airport, fly to Buffalo Niagara International Airport, line 40 bus

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Buffalo Niagara International Airport (BUF)plane plane IAD - BUF
    3. Take the bus from Ellicott Street & MTC Static to Main Street & Pine Avenuebus bus
    6h 54m
    $72–480

  7. Bus to Baltimore-Washington International Airport, fly to Rochester, train

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Rochester (ROC)plane plane BWI - ROC
    3. Take the train from Rochester to Niagara Falls Amtrak Stationtrain train
    6h 31m
    $207–946

  8. Bus to Washington Dulles International Airport, fly to Rochester, train

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Rochester (ROC)plane plane IAD - ROC
    3. Take the train from Rochester to Niagara Falls Amtrak Stationtrain train
    7h 41m
    $132–817

  9. Bus to Washington Dulles International Airport, fly to Toronto Island Airport, bus

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Toronto Island Airport (YTZ)plane plane IAD - YTZ
    3. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    8h 24m
    $141–630

  10. Bus to Washington Dulles International Airport, fly to Toronto Pearson International Airport, bus

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Toronto Pearson International Airport (YYZ)plane plane IAD - YYZ
    3. Take the bus from Toronto Union Station to Niagara Falls, ONbus bus
    8h 42m
    $567–1,189

  11. Bus via Pittsburgh

    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    14h 28m
    $74–242

  12. Bus, train

    1. Take the bus from Frederick Transit Center to BWI Amtrak Stationbus bus
    2. Take the train from BWI Thurgood Marshall to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Stationtrain train
    15h 8m
    $233–1,084

  13. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the bus from Washington Union Station to Ithacabus bus
    3. Take the bus from Ithaca to Niagara Falls USAbus bus
    17h 50m
    $97–177

Frederick to Niagara Falls by bus (Greyhound)

Calendar7Weekly Buses
Duration13h 33mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Frederick to Niagara Falls.ExpandLaunch map view
  • Distance: 363.7 mi
  • Duration: 5h 48m

What companies run services between Frederick, MD, USA and Niagara Falls, NY, USA?

You can take a bus from Frederick Bus Station to Main Street & Pine Avenue via Cleveland Bus Station, Buffalo, and Ellicott Street & MTC Static in around 13h 33m. Alternatively, you can take a train from FREDERICK MARC eb to Niagara Falls Amtrak Station via Washington Union Station and Ny Moynihan Train Hall At Penn Station in around 15h 6m.

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