There are 9 ways to get from Frederick to Portland by bus, plane, train, bus (Flixbus, Greyhound, Amtrak), car, train (Amtrak), or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly
best- Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
- Fly from Baltimore-Washington International Airport (BWI) to Portland (PWM)plane BWI - PWM
3h 30m$144–526Bus to Washington Dulles International Airport, fly
cheapest- Take the bus from Frederick Transit Station to Market St & Harrison Stbus
- Fly from Washington Dulles International Airport (IAD) to Portland (PWM)plane IAD - PWM
4h 49m$74–415Bus, train
- Take the bus from Frederick Transit Center to BWI Amtrak Stationbus
- Take the train from BWI Thurgood Marshall to Bostontrain
- Take the bus from Boston, MA - South Station to Portland, MEbus
10h 52m$219–412Bus
- Take the bus from Frederick to Baltimorebus
- Take the bus from Baltimore Downtown Bus Station to Bostonbus
- Take the bus from Boston, MA - South Station to Portland, MEbus
12h 20m$114–272Drive 539.6 mi
- Drive from Frederick to Portlandcar 539.6 mi
9h 58m$99–143Train to Ronald Reagan Washington National Airport, fly
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Portland (PWM)plane DCA - PWM
4h 30m$117–667Train, bus
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain
- Take the train from Washington Union Station to Bostontrain
- Take the bus from Boston, MA - South Station to Portland, MEbus
11h 41m$163–357Train
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain
- Take the train from Washington Union Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
- Take the train from Boston to Portlandtrain
12h 58m$185–390Bus via New York
- Take the bus from Frederick to Baltimorebus
- Take the bus from Baltimore Downtown Bus Station to New York Midtownbus
- Take the bus from New York Midtown to City of Portlandbus
13h 13m$133–262
Frederick to Portland by bus and train
Questions & Answers
The cheapest way to get from Frederick to Portland is to drive which costs $95 - $150 and takes 9h 58m.
The fastest way to get from Frederick to Portland is to bus and fly which takes 3h 30m and costs $140 - $550.
No, there is no direct bus from Frederick to Portland. However, there are services departing from Frederick and arriving at Portland, ME via Baltimore Downtown Bus Station and Boston, MA - South Station. The journey, including transfers, takes approximately 12h 20m.
No, there is no direct train from Frederick to Portland. However, there are services departing from FREDERICK MARC eb and arriving at Portland via Washington Union Station, Ny Moynihan Train Hall At Penn Station, Back Bay and Boston. The journey, including transfers, takes approximately 12h 58m.
The distance between Frederick and Portland is 502 miles. The road distance is 542.8 miles.
The best way to get from Frederick to Portland without a car is to bus and train which takes 10h 52m and costs $210 - $420.
It takes approximately 3h 30m to get from Frederick to Portland, including transfers.
Frederick to Portland bus services, operated by Jefferson Lines, depart from Frederick station.
Frederick to Portland train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.
The best way to get from Frederick to Portland is to bus which takes 12h 20m and costs $110 - $280. Alternatively, you can train, which costs $180 - $390 and takes 12h 58m.
What companies run services between Frederick, MD, USA and Portland, ME, USA?
You can take a bus from Frederick to Portland, ME via Baltimore Downtown Bus Station, Boston, and Boston, MA - South Station in around 12h 20m. Alternatively, you can take a train from FREDERICK MARC eb to Portland via Washington Union Station, Ny Moynihan Train Hall At Penn Station, Boston, Back Bay, North Station, and Boston in around 12h 58m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Portland
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $75–440
- Website
- aa.com
Flights from Ronald Reagan Washington National Airport to Portland
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $110–650
Flights from Ronald Reagan Washington National Airport to Portland via New York La Guardia
- Ave. Duration
- 3h 41m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
Flights from Ronald Reagan Washington National Airport to Portland via Philadelphia
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $110–650
- Website
- united.com
Flights from Washington Dulles International Airport to Portland
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $70–390
- Website
- delta.com
Flights from Ronald Reagan Washington National Airport to Portland via New York La Guardia
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $110–650
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from BWI Thurgood Marshall to Boston
- Ave. Duration
- 6h 50m
- Frequency
- 5 times a day
- Estimated price
- $95–900
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $95–550
- First Class
- $300–900
Train from Washington Union Station to Boston
- Ave. Duration
- 6h 57m
- Frequency
- Every 4 hours
- Estimated price
- $100–900
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $100–550
- First Class
- $310–900
Train from Washington Union Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h
- Frequency
- Hourly
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 36m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from BWI Thurgood Marshall to Boston
- Ave. Duration
- 11h 30m
- Frequency
- Every 3 hours
- Estimated price
- $130–280
- Website
- https://www.amtrak.com/home.html
Train from Washington Union Station to Boston
- Ave. Duration
- 12h 5m
- Frequency
- Every 3 hours
- Estimated price
- $140–300
- Website
- https://www.amtrak.com/home.html
Train from Washington Union Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 7m
- Frequency
- Hourly
- Estimated price
- $70–150
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 14m
- Frequency
- Every 3 hours
- Estimated price
- $75–150
- Website
- https://www.amtrak.com/home.html
Train from Boston to Portland
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $35–75
- Website
- https://www.amtrak.com/home.html
- Phone
- 1-866-743-3682
- Website
- mta.maryland.gov
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–12
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–12
- Phone
- +1 410-912-6000
- [email protected]
- Website
- bayrunnershuttle.com
Bus from Frederick Bayrunner Office to Baltimore Airport
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $65–90
- Schedules at
- bayrunnershuttle.com
Bus from Frederick Transit Center to BWI Amtrak Station
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Estimated price
- $65–90
- Schedules at
- bayrunnershuttle.com
Bus from Frederick to Baltimore
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $65–90
- Schedules at
- bayrunnershuttle.com
Bus from Frederick to Baltimore
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $65–90
- Schedules at
- bayrunnershuttle.com
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Frederick Transit Center to BWI Amtrak Station
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Estimated price
- $16–23
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800 639 3317
- [email protected]
- Website
- concordcoachlines.com
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $22–30
- Website
- https://concordcoachlines.com
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $22–30
- Website
- https://concordcoachlines.com
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $22–30
- Website
- https://concordcoachlines.com
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $21–45
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $21–45
Bus from Boston, MA - South Station to Portland, ME
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $21–45
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Frederick to Baltimore
- Ave. Duration
- 50 min
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Book at
- https://www.jeffersonlines.com
- Adult
- $22–35
Bus from Baltimore Downtown Bus Station to Boston
- Ave. Duration
- 8h 15m
- Frequency
- Twice daily
- Estimated price
- $100–150
- Book at
- https://www.jeffersonlines.com
- Adult
- $100–150
Bus from Frederick to Baltimore
- Ave. Duration
- 50 min
- Frequency
- 3 times a day
- Estimated price
- $22–35
- Book at
- https://www.jeffersonlines.com
- Adult
- $22–35
Bus from Baltimore Downtown Bus Station to New York Midtown
- Ave. Duration
- 3h 30m
- Frequency
- Every 4 hours
- Estimated price
- $60–85
- Book at
- https://www.jeffersonlines.com
- Adult
- $60–85
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Baltimore Downtown Bus Station to Boston
- Ave. Duration
- 8h 45m
- Frequency
- Twice daily
- Estimated price
- $70–120
- Schedules at
- flixbus.com
Bus from Baltimore Downtown Bus Station to New York Midtown
- Ave. Duration
- 3h 30m
- Frequency
- Every 3 hours
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Bus from New York Midtown to City of Portland
- Ave. Duration
- 7h 11m
- Frequency
- Once daily
- Estimated price
- $50–90
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Baltimore Downtown Bus Station to Boston
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.greyhound.com/
- Phone
- +1 703-771-5665
- Website
- loudoun.gov
Bus from Frederick Transit Station to Market St & Harrison St
- Ave. Duration
- 58 min
- Frequency
- Once daily
- Estimated price
- $1–11
- Schedules at
- loudoun.gov
- Local & Metro
- $1–2
- Commuter
- $11
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More Questions & Answers
Frederick to Portland bus services, operated by Jefferson Lines, arrive at Baltimore station.
Frederick to Portland train services, operated by Maryland Transit, arrive at Washington Union Station.
Yes, the driving distance between Frederick to Portland is 543 miles. It takes approximately 9h 58m to drive from Frederick to Portland.
Book your Frederick to Portland bus tickets online with Omio.
There are 442+ hotels available in Portland.





















