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How to get fromFrederick to Portsmouthby bus, plane, train, bus (Flixbus), car, or bus (Greyhound)

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There are 11 ways to get from Frederick to Portsmouth by bus, plane, train, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Boston Logan Airport, bus

    best
    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Boston Logan Airport (BOS)plane plane BWI - BOS
    3. Take the bus from Boston to Portsmouthbus bus
    6h 15m
    $224–1,114

  2. Bus to Washington Dulles International Airport, fly to Portland, bus

    cheapest
    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Portland (PWM)plane plane IAD - PWM
    3. Take the bus from City of Portland to Portsmouth Bus Stopbus bus
    7h 42m
    $83–434

  3. Bus, train

    1. Take the bus from Frederick Transit Center to BWI Amtrak Stationbus bus
    2. Take the train from BWI Thurgood Marshall to Bostontrain train
    3. Take the bus from Boston to Portsmouth Bus Stopbus bus
    10h 37m
    $206–384

  4. Bus

    1. Take the bus from Frederick Bayrunner Office to Baltimore Downtown Bus Terminal, Baltimore, MDbus bus
    2. Take the bus from Baltimore Downtown Bus Station to New York Midtownbus bus
    3. Take the bus from New York Midtown to Portsmouth Bus Stopbus bus
    12h 6m
    $148–226

  5. Drive 490.1 mi

    1. Drive from Frederick to Portsmouthcar car 490.1 mi
    9h 10m
    $90–130

  6. Bus to Baltimore-Washington International Airport, fly to Portland, bus

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Portland (PWM)plane plane BWI - PWM
    3. Take the bus from City of Portland to Portsmouth Bus Stopbus bus
    6h 22m
    $153–556

  7. Bus to Washington Dulles International Airport, fly to Boston Logan Airport, bus

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Boston Logan Airport (BOS)plane plane IAD - BOS
    3. Take the bus from Boston to Portsmouthbus bus
    7h 33m
    $519–1,152

  8. Bus to Baltimore-Washington International Airport, fly to Manchester Airport, bus

    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Manchester Airport (MHT)plane plane BWI - MHT
    3. Take the bus from Boston Manchester Airport to Bostonbus bus
    4. Take the bus from Boston to Portsmouth Bus Stopbus bus
    7h 55m
    $144–508

  9. Train to Ronald Reagan Washington National Airport, fly to Manchester Airport, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Manchester Airport (MHT)plane plane DCA - MHT
    3. Take the bus from Boston Manchester Airport to Bostonbus bus
    4. Take the bus from Boston to Portsmouth Bus Stopbus bus
    9h 1m
    $117–649

  10. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Bostontrain train
    3. Take the bus from Boston to Portsmouth Bus Stopbus bus
    11h 26m
    $150–329

  11. Bus via Boston

    1. Take the bus from Frederick Bus Station to Baltimore Downtown Bus Stationbus bus
    2. Take the bus from Baltimore Downtown Bus Station to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Bostonbus bus
    4. Take the bus from Boston to Portsmouthbus bus
    14h 55m
    $178–314

Frederick to Portsmouth by bus and train

Calendar30Weekly Services
Duration10h 37mAverage Duration
Ticket$206Cheapest Price
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Questions & Answers

Map of how to get from Frederick to Portsmouth.ExpandLaunch map view
  • Distance: 474 mi
  • Duration: 6h 15m

What companies run services between Frederick, MD, USA and Portsmouth, NH, USA?

You can take a bus from Frederick Bayrunner Office to Portsmouth Bus Stop via Baltimore Downtown Bus Station and New York Midtown in around 12h 6m.

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