There are 9 ways to get from Frederick to San Antonio by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, subway, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly to San Antonio International Airport
best- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to San Antonio International Airport (SAT)plane BWI - SAT
6h 41m$269–1,006Train, subway to Washington Dulles International Airport, fly to San Antonio International Airport
cheapest- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to San Antonio International Airport (SAT)plane IAD - SAT
7h 47m$168–818Bus
- Take the bus from Frederick Bus Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Houston Bus Stationbus
- Take the bus from Houston Bus Station to San Antonio Bus Stationbus
36h 30m$256–431Train
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain
- Take the train from Washington Union Station to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to San Antonio Stationtrain
46h 27m$422–1,042Drive 1,581.7 mi
- Drive from Frederick to San Antoniocar 1,581.7 mi
25h 34m$289–417Train to Ronald Reagan Washington National Airport, fly to San Antonio International Airport
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to San Antonio International Airport (SAT)plane DCA - SAT
7h 19m$258–1,219Bus to Baltimore-Washington International Airport, fly to Austin-Bergstrom International Airport, bus
- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to Austin-Bergstrom International Airport (AUS)plane BWI - AUS
- Take the bus from Austin, TX - UT Austin to San Antonio, TX - E Commerce Stbus
9h 32m$417–884Train to Ronald Reagan Washington National Airport, fly to Austin-Bergstrom International Airport, bus
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Austin-Bergstrom International Airport (AUS)plane DCA - AUS
- Take the bus from Austin, TX - UT Austin to San Antonio, TX - E Commerce Stbus
10h 3m$196–997Bus via Chicago
- Take the bus from Frederick Bus Station to Chicago Bus Stationbus Greyhound US0164
- Take the bus from Chicago to Tornado Bus Co - San Antoniobus Chicago
41h 1m$331–453
Frederick to San Antonio by bus
Comparing Your Travel Options
The cheapest way to get from Frederick to San Antonio is to bus which costs $250 - $440 and takes 36h 30m.
The fastest way to get from Frederick to San Antonio is to bus and fly which takes 6h 41m and costs $260 - $1,100.
No, there is no direct bus from Frederick station to San Antonio station. However, there are services departing from Frederick Bus Station and arriving at San Antonio Bus Station via Washington Union Station, Atlanta Bus Station and Houston Bus Station. The journey, including transfers, takes approximately 36h 30m.
No, there is no direct train from Frederick to San Antonio station. However, there are services departing from FREDERICK MARC eb and arriving at San Antonio Station via Washington Union Station and New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 46h 27m.
The distance between Frederick and San Antonio is 1483 miles. The road distance is 1591 miles.
The best way to get from Frederick to San Antonio without a car is to bus which takes 36h 30m and costs $250 - $440.
It takes approximately 6h 41m to get from Frederick to San Antonio, including transfers.
Frederick to San Antonio bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Frederick to San Antonio train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.
The best way to get from Frederick to San Antonio is to bus which takes 36h 30m and costs $250 - $440. Alternatively, you can train, which costs $420 - $1,100 and takes 46h 27m.
What companies run services between Frederick, MD, USA and San Antonio, TX, USA?
You can take a bus from Frederick Bus Station to San Antonio Bus Station via Washington Union Station, Atlanta Bus Station, and Houston Bus Station in around 36h 30m. Alternatively, you can take a train from FREDERICK MARC eb to San Antonio Station via Washington Union Station and New Orleans Union Passenger Terminal in around 46h 27m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to San Antonio International Airport
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- $190–900
Flights from Baltimore-Washington International Airport to San Antonio International Airport via Dallas
- Ave. Duration
- 5h 8m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $190–900
Flights from Baltimore-Washington International Airport to San Antonio International Airport via Houston Hobby Apt
- Ave. Duration
- 5h 15m
- When
- Tuesday and Wednesday
- Estimated price
- $190–900
Flights from Baltimore-Washington International Airport to San Antonio International Airport via St. Louis
- Ave. Duration
- 5h 25m
- When
- Monday to Wednesday
- Estimated price
- $200–950
Flights from Ronald Reagan Washington National Airport to San Antonio International Airport via Nashville
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $250–1,200
Flights from Ronald Reagan Washington National Airport to San Antonio International Airport via Dallas
- Ave. Duration
- 5h 21m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $260–1,200
Flights from Ronald Reagan Washington National Airport to San Antonio International Airport via St. Louis
- Ave. Duration
- 5h 20m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $270–1,300
Flights from Ronald Reagan Washington National Airport to San Antonio International Airport via New Orleans
- Ave. Duration
- 5h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $260–1,300
Flights from Baltimore-Washington International Airport to Austin-Bergstrom International Airport
- Ave. Duration
- 3h 26m
- When
- Every day
- Estimated price
- $160–800
Flights from Baltimore-Washington International Airport to Austin-Bergstrom International Airport via Dallas
- Ave. Duration
- 5h 8m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $160–800
Flights from Baltimore-Washington International Airport to Austin-Bergstrom International Airport via Nashville
- Ave. Duration
- 5h 22m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–800
Flights from Baltimore-Washington International Airport to Austin-Bergstrom International Airport via Pittsburgh
- Ave. Duration
- 5h 40m
- When
- Tuesday and Wednesday
- Estimated price
- $170–800
Flights from Ronald Reagan Washington National Airport to Austin-Bergstrom International Airport
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Ronald Reagan Washington National Airport to Austin-Bergstrom International Airport via Dallas
- Ave. Duration
- 5h 16m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $220–1,100
Flights from Ronald Reagan Washington National Airport to Austin-Bergstrom International Airport via New Orleans
- Ave. Duration
- 5h 30m
- When
- Sunday
- Estimated price
- $230–1,100
Flights from Ronald Reagan Washington National Airport to Austin-Bergstrom International Airport via Nashville
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Ronald Reagan Washington National Airport to Austin-Bergstrom International Airport via Houston Hobby Apt
- Ave. Duration
- 5h 55m
- When
- Monday, Thursday, and Friday
- Estimated price
- $220–1,100
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- Maryland Transit
- Standard Fare
- $2–12
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
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Booking & Getting There
Frederick to San Antonio bus services, operated by Greyhound USA, arrive at Washington Union Station.
San Antonio is 1h behind Frederick. It is currently 6:12 AM in Frederick and 5:12 AM in San Antonio.
Frederick to San Antonio train services, operated by Maryland Transit, arrive at Washington Union Station.
Yes, the driving distance between Frederick to San Antonio is 1591 miles. It takes approximately 25h 34m to drive from Frederick to San Antonio.
Book your Frederick to San Antonio bus tickets online with Omio and FlixBus.
There are 1332+ hotels available in San Antonio.








