There are 7 ways to get from Frederick to San Diego by bus, plane, train, bus (Greyhound, Amtrak), car, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly
best- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to San Diego International Airport (SAN)plane BWI - SAN
7h 40m$427–754Bus to Washington Dulles International Airport, fly
cheapest- Take the bus from Frederick Transit Station to Market St & Harrison Stbus
- Fly from Washington Dulles International Airport (IAD) to San Diego International Airport (SAN)plane IAD - SAN
8h 27m$174–725Bus, train
- Take the bus from Frederick Bus Station to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to San Diegotrain
2d 14h$682–1,535Bus
- Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus
- Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
- Take the bus from Los Angeles to San Diegobus
2d 15h$450–764Drive 2,557.2 mi
- Drive from Frederick to San Diegocar 2,557.2 mi
42h 20m$467–675Train to Ronald Reagan Washington National Airport, fly
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to San Diego International Airport (SAN)plane DCA - SAN
8h 29m$177–567Train
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the train from Rockville Amtrak to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to San Diegotrain
2d 18h$779–1,810
Frederick to San Diego by bus, foot, and train
Questions & Answers
The cheapest way to get from Frederick to San Diego is to train and fly which costs $170 - $600 and takes 8h 29m.
The fastest way to get from Frederick to San Diego is to bus and fly which takes 7h 40m and costs $420 - $800.
No, there is no direct bus from Frederick station to San Diego. However, there are services departing from Frederick Bus Station and arriving at San Diego via Pittsburgh Intermodal Station, St Louis Bus Station and Los Angeles. The journey, including transfers, takes approximately 2 days 15h.
No, there is no direct train from Frederick to San Diego. However, there are services departing from FREDERICK MARC eb and arriving at San Diego via Rockville Amtrak, Chicago Union Station and Fullerton Amtrak Station. The journey, including transfers, takes approximately 2 days 18h.
The distance between Frederick and San Diego is 2364 miles. The road distance is 2572.2 miles.
The best way to get from Frederick to San Diego without a car is to bus and train which takes 2 days 14h and costs $650 - $1,600.
It takes approximately 7h 40m to get from Frederick to San Diego, including transfers.
Frederick to San Diego bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Frederick to San Diego train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.
The best way to get from Frederick to San Diego is to bus which takes 2 days 15h and costs $450 - $800. Alternatively, you can train, which costs $750 - $1,900 and takes 2 days 18h.
What companies run services between Frederick, MD, USA and San Diego, CA, USA?
You can take a bus from Frederick Bus Station to San Diego via Pittsburgh Intermodal Station, St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 15h. Alternatively, you can take a train from FREDERICK MARC eb to San Diego via Rockville Amtrak, Chicago Union Station, and Fullerton Amtrak Station in around 2d 18h.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to San Diego International Airport
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $200–850
Flights from Baltimore-Washington International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 7h 5m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $200–850
Flights from Baltimore-Washington International Airport to San Diego International Airport via Dallas
- Ave. Duration
- 7h 6m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $210–850
Flights from Baltimore-Washington International Airport to San Diego International Airport via Kansas City
- Ave. Duration
- 7h 5m
- When
- Tuesday and Wednesday
- Estimated price
- $200–850
Flights from Baltimore-Washington International Airport to San Diego International Airport via Denver
- Ave. Duration
- 7h 7m
- When
- Monday to Saturday
- Estimated price
- $200–850
Flights from Baltimore-Washington International Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 7h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–850
Flights from Ronald Reagan Washington National Airport to San Diego International Airport via Dallas
- Ave. Duration
- 7h 27m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $280–1,200
Flights from Ronald Reagan Washington National Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 8h
- When
- Sunday and Saturday
- Estimated price
- $280–1,200
Flights from Ronald Reagan Washington National Airport to San Diego International Airport via Kansas City
- Ave. Duration
- 10h 20m
- When
- Tuesday and Wednesday
- Estimated price
- $270–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $550–1,300
- Website
- Amtrak
Train from Fullerton Amtrak Station to San Diego
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- $27–60
- Website
- Amtrak
Train from Rockville Amtrak to Chicago Union Station
- Ave. Duration
- 17h 24m
- Frequency
- Once daily
- Estimated price
- $200–440
- Website
- Amtrak
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $550–1,300
- Website
- Amtrak
Train from Fullerton Amtrak Station to San Diego
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- $27–60
- Website
- Amtrak
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Frederick to San Diego bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
San Diego is 3h behind Frederick. It is currently 7:08 AM in Frederick and 4:08 AM in San Diego.
Frederick to San Diego train services, operated by Maryland Transit, arrive at ROCKVILLE MARC eb station.
Yes, the driving distance between Frederick to San Diego is 2572 miles. It takes approximately 42h 20m to drive from Frederick to San Diego.
Book your Frederick to San Diego bus tickets online with Omio.
There are 2376+ hotels available in San Diego.











