There are 8 ways to get from Frederick to San Diego by bus, plane, train, bus (Greyhound, Amtrak), car, subway, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly
best- Take the bus from Frederick to Baltimorebus
- Fly from Baltimore-Washington International Airport (BWI) to San Diego International Airport (SAN)plane BWI - SAN
8h$427–754Train, subway to Washington Dulles International Airport, fly
cheapest- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to San Diego International Airport (SAN)plane IAD - SAN
8h 51m$156–666Bus, train
- Take the bus from Frederick Bus Station to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to San Diegotrain
2d 14h$1,372–2,162Bus
- Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus
- Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
- Take the bus from Los Angeles to San Diegobus
2d 15hDrive 2,557.2 mi
- Drive from Frederick to San Diegocar 2,557.2 mi
42h 21m$467–675Train to Ronald Reagan Washington National Airport, fly
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to San Diego International Airport (SAN)plane DCA - SAN
8h 28m$176–567Bus, train to Philadelphia International Airport, fly
- Take the bus from Frederick Transit Center to BWI Amtrak Stationbus
- Take the train from BWI Thurgood Marshall to 30th Street Stationtrain
- Fly from Philadelphia International Airport (PHL) to San Diego International Airport (SAN)plane PHL - SAN
10h 37mTrain
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the train from Rockville Amtrak to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain
- Take the train from Fullerton Amtrak Station to San Diegotrain
2d 18h$1,667–2,650
Frederick to San Diego by bus, foot, and train
Comparing Your Travel Options
The cheapest way to get from Frederick to San Diego is to train and fly which costs $170 - $600 and takes 8h 28m.
The fastest way to get from Frederick to San Diego is to bus and fly which takes 8h and costs $420 - $800.
No, there is no direct bus from Frederick station to San Diego. However, there are services departing from Frederick Bus Station and arriving at San Diego via Pittsburgh Intermodal Station, St Louis Bus Station and Los Angeles. The journey, including transfers, takes approximately 2 days 15h.
No, there is no direct train from Frederick to San Diego. However, there are services departing from FREDERICK MARC eb and arriving at San Diego via Rockville Amtrak, Chicago Union Station and Fullerton Amtrak Station. The journey, including transfers, takes approximately 2 days 18h.
The distance between Frederick and San Diego is 2364 miles. The road distance is 2572.2 miles.
The best way to get from Frederick to San Diego without a car is to bus and train which takes 2 days 14h and costs $1,300 - $2,200.
It takes approximately 8h to get from Frederick to San Diego, including transfers.
Frederick to San Diego bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Frederick to San Diego train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.
The best way to get from Frederick to San Diego is to bus which takes 2 days 15h and costs . Alternatively, you can train, which costs $1,600 - $2,700 and takes 2 days 18h.
What companies run services between Frederick, MD, USA and San Diego, CA, USA?
You can take a bus from Frederick Bus Station to San Diego via Pittsburgh Intermodal Station, St Louis Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 15h. Alternatively, you can take a train from FREDERICK MARC eb to San Diego via Rockville Amtrak, Chicago Union Station, and Fullerton Amtrak Station in around 2d 18h.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to San Diego International Airport
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $180–750
Flights from Baltimore-Washington International Airport to San Diego International Airport via St. Louis
- Ave. Duration
- 6h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–750
Flights from Baltimore-Washington International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 7h 22m
- When
- Sunday, Tuesday, and Wednesday
- Estimated price
- $180–750
Flights from Baltimore-Washington International Airport to San Diego International Airport via Dallas
- Ave. Duration
- 7h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–800
Flights from Baltimore-Washington International Airport to San Diego International Airport via Denver
- Ave. Duration
- 7h 25m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $180–800
Flights from Baltimore-Washington International Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 7h 27m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $180–800
Flights from Ronald Reagan Washington National Airport to San Diego International Airport via Kansas City
- Ave. Duration
- 7h 5m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $230–1,000
Flights from Ronald Reagan Washington National Airport to San Diego International Airport via Las Vegas
- Ave. Duration
- 7h 57m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $240–1,000
Flights from Ronald Reagan Washington National Airport to San Diego International Airport via Dallas
- Ave. Duration
- 8h 2m
- When
- Every day
- Estimated price
- $240–1,100
Flights from Philadelphia International Airport to San Diego International Airport via St. Louis
- Ave. Duration
- 7h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–850
Flights from Philadelphia International Airport to San Diego International Airport via Chicago Midway
- Ave. Duration
- 7h 42m
- When
- Saturday
- Estimated price
- $200–850
Flights from Philadelphia International Airport to San Diego International Airport via Denver
- Ave. Duration
- 7h 53m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $200–850
Flights from Philadelphia International Airport to San Diego International Airport via Dallas
- Ave. Duration
- 7h 55m
- When
- Saturday
- Estimated price
- $200–850
- Website
- united.com
Flights from Baltimore-Washington International Airport to San Diego International Airport via Denver
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $180–800
Flights from Ronald Reagan Washington National Airport to San Diego International Airport via Denver
- Ave. Duration
- 7h 21m
- When
- Every day
- Estimated price
- $240–1,000
Flights from Washington Dulles International Airport to San Diego International Airport
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $150–650
Flights from Washington Dulles International Airport to San Diego International Airport via Denver
- Ave. Duration
- 7h 38m
- When
- Every day
- Estimated price
- $150–700
Flights from Philadelphia International Airport to San Diego International Airport via Denver
- Ave. Duration
- 7h 49m
- When
- Every day
- Estimated price
- $200–850
- Website
- aa.com
Flights from Ronald Reagan Washington National Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 8h 25m
- When
- Every day
- Estimated price
- $230–1,000
Flights from Washington Dulles International Airport to San Diego International Airport
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $220–900
Flights from Philadelphia International Airport to San Diego International Airport
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $190–850
Flights from Philadelphia International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 7h 47m
- When
- Every day
- Estimated price
- $190–850
- Website
- alaskaair.com
Flights from Ronald Reagan Washington National Airport to San Diego International Airport
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $340–1,400
Flights from Washington Dulles International Airport to San Diego International Airport
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $220–900
- Website
- flyfrontier.com
Flights from Ronald Reagan Washington National Airport to San Diego International Airport via Denver
- Ave. Duration
- 8h 56m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $240–370
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $1,200–1,900
- Website
- Amtrak
Train from Fullerton Amtrak Station to San Diego
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from BWI Thurgood Marshall to 30th Street Station
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
Train from Rockville Amtrak to Chicago Union Station
- Ave. Duration
- 17h 24m
- Frequency
- Once daily
- Estimated price
- $410–650
- Website
- Amtrak
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $1,200–1,900
- Website
- Amtrak
Train from Fullerton Amtrak Station to San Diego
- Ave. Duration
- 2h 26m
- Frequency
- Hourly
- Estimated price
- $55–90
- Website
- Amtrak
- Phone
- 1-866-743-3682
- Website
- Maryland Transit
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- Maryland Transit
- Standard Fare
- $2–10
Subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platform
- Ave. Duration
- 51 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from BWI Thurgood Marshall to 30th Street Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
- Phone
- +1 410-912-6000
- [email protected]
- Website
- BayRunner Shuttle
Bus from Frederick to Baltimore
- Ave. Duration
- 1h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–110
- Schedules at
- BayRunner Shuttle
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Frederick Bus Station to Chicago Bus Station
- Ave. Duration
- 15h 25m
- Frequency
- Once daily
- Estimated price
- $110–180
- Website
- Greyhound
Bus from Frederick Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Greyhound
Bus from Pittsburgh Intermodal Station to St Louis Bus Station
- Ave. Duration
- 12h 55m
- Frequency
- 3 times a day
- Estimated price
- $100–160
- Website
- Greyhound
Bus from St Louis Bus Station to Los Angeles Union Station
- Ave. Duration
- 40h 30m
- Frequency
- Once daily
- Estimated price
- $330–500
- Website
- Greyhound
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Los Angeles to San Diego
- Ave. Duration
- 3h
- Frequency
- Once daily
- Website
- Amtrak
Bus from Frederick Transit Center to BWI Amtrak Station
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Website
- Amtrak
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Booking & Getting There
Frederick to San Diego bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
San Diego is 3h behind Frederick. It is currently 11:19 PM in Frederick and 8:19 PM in San Diego.
Frederick to San Diego train services, operated by Maryland Transit, arrive at ROCKVILLE MARC eb station.
Yes, the driving distance between Frederick to San Diego is 2572 miles. It takes approximately 42h 21m to drive from Frederick to San Diego.
Book your Frederick to San Diego bus tickets online with Omio.
There are 2375+ hotels available in San Diego.





















