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How to get fromFrederick to South Carolinaby bus, plane, train (Amtrak), car, taxi, or train

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There are 8 ways to get from Frederick to South Carolina by bus, plane, train (Amtrak), car, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Charleston International Airport

    best
    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Charleston International Airport (CHS)plane plane BWI - CHS
    5h 8m

  2. Drive 539.4 mi

    cheapest
    1. Drive from Frederick to Charlestoncar car 539.4 mi
    10h 5m
    $99–143

  3. Train

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train Marc
    2. Take the train from Washington Union Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    12h 17m
    $192–382

  4. Bus to Washington Dulles International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Greenville–Spartanburg International Airport (GSP)plane plane IAD - GSP
    4h 57m
    $119–550

  5. Bus to Washington Dulles International Airport, fly to Charlotte Douglas International Airport, taxi

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Charlotte Douglas International Airport (CLT)plane plane IAD - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    5h 7m
    $204–425

  6. Train to Ronald Reagan Washington National Airport, fly to Columbia

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Columbia (CAE)plane plane DCA - CAE
    5h 51m
    $239–1,419

  7. Bus to Washington Dulles International Airport, fly to Charleston International Airport

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Charleston International Airport (CHS)plane plane IAD - CHS
    5h 56m
    $556–1,127

  8. Bus to Washington Dulles International Airport, fly to Columbia

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Columbia (CAE)plane plane IAD - CAE
    6h
    $136–827

Baltimore-Washington International Airport (BWI) to Charleston International Airport (CHS) flights

Calendar41Weekly Planes
Duration2h 20mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Frederick to South Carolina.ExpandLaunch map view
  • Distance: 540.7 mi
  • Duration: 5h 8m

What companies run services between Frederick, MD, USA and South Carolina, USA?

You can take a train from FREDERICK MARC eb to Charleston via Washington Union Station and Charleston Amtrak Station in around 12h 17m.

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