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How to get fromFrederick to South Carolinaby bus, plane, train (Amtrak), car, train, subway, or taxi

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There are 8 ways to get from Frederick to South Carolina by bus, plane, train (Amtrak), car, train, subway, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Charleston International Airport

    best
    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Charleston International Airport (CHS)plane plane BWI - CHS
    5h 7m
    $829–1,206

  2. Train, subway to Washington Dulles International Airport, fly to Columbia

    cheapest
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Columbia (CAE)plane plane IAD - CAE
    6h 24m
    $63–368

  3. Train

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train Marc
    2. Take the train from Washington Union Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    12h 17m
    $162–372

  4. Drive  539.4 mi

    1. Drive from Frederick to Charlestoncar car 539.4 mi
    10h 5m
    $99–143

  5. Train, subway to Washington Dulles International Airport, fly to Greenville–Spartanburg International Airport

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Greenville–Spartanburg International Airport (GSP)plane plane IAD - GSP
    5h 22m
    $121–611

  6. Train, subway to Washington Dulles International Airport, fly to Charlotte Douglas International Airport, taxi

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Charlotte Douglas International Airport (CLT)plane plane IAD - CLT
    4. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    5h 31m
    $186–416

  7. Train to Ronald Reagan Washington National Airport, fly to Columbia

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Columbia (CAE)plane plane DCA - CAE
    5h 54m
    $93–569

  8. Train, subway to Washington Dulles International Airport, fly to Charleston International Airport

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Charleston International Airport (CHS)plane plane IAD - CHS
    6h 17m
    $78–448

Baltimore-Washington International Airport (BWI) to Charleston International Airport (CHS) flights

Calendar63Weekly Planes
Duration2h 38mAverage Duration
Ticket$84Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Frederick to South Carolina.ExpandLaunch map view
  • Distance: 540.7 mi
  • Duration: 5h 7m

What companies run services between Frederick, MD, USA and South Carolina, USA?

You can take a train from FREDERICK MARC eb to Charleston via Washington Union Station and Charleston Amtrak Station in around 12h 17m.

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