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How to get fromFrederick to West Lafayetteby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or subway

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There are 8 ways to get from Frederick to West Lafayette by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Indianapolis, bus

    best
    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Indianapolis (IND)plane plane BWI - IND
    3. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    6h 25m
    $505–1,044

  2. Bus

    cheapest
    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Pittsburgh Intermodal Station to Lafayette Bus Stopbus bus FlixBus N2642 / ...
    13h 55m
    $91–143

  3. Train

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train Marc
    2. Take the train from Washington Union Station to Lafayette Amtrak Stationtrain train Cardinal
    23h 2m
    $432–712

  4. Drive  579.1 mi

    1. Drive from Frederick to West Lafayettecar car 579.1 mi
    10h 20m
    $106–153

  5. Train to Ronald Reagan Washington National Airport, fly to Indianapolis, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Indianapolis (IND)plane plane DCA - IND
    3. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    7h 1m
    $984–1,657

  6. Train, subway to Washington Dulles International Airport, fly to Indianapolis, bus

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Indianapolis (IND)plane plane IAD - IND
    4. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus
    7h 27m
    $584–1,156

  7. Bus to Baltimore-Washington International Airport, fly to Chicago Midway International Airport, train

    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Chicago Midway International Airport (MDW)plane plane BWI - MDW
    3. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    9h 13m
    $264–519

  8. Train to Ronald Reagan Washington National Airport, fly to Chicago Midway International Airport, train

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Chicago Midway International Airport (MDW)plane plane DCA - MDW
    3. Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain train
    9h 39m
    $173–732

Frederick to West Lafayette by bus

Calendar9Weekly Buses
Duration13h 55mAverage Duration
Ticket$91Cheapest Price
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Comparing Your Travel Options

Map of how to get from Frederick to West Lafayette.ExpandLaunch map view
  • Distance: 644.5 mi
  • Duration: 6h 25m

What companies run services between Frederick, MD, USA and West Lafayette, IN, USA?

You can take a bus from Frederick Bus Station to Lafayette Bus Stop via Pittsburgh Intermodal Station in around 13h 55m. Alternatively, you can take a train from FREDERICK MARC eb to Lafayette Amtrak Station via Washington Union Station in around 23h 2m.

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