There are 8 ways to get from Frederick to West Lafayette by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly to Indianapolis, bus
best- Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
- Fly from Baltimore-Washington International Airport (BWI) to Indianapolis (IND)plane BWI - IND
- Take the bus from Indianapolis Airport to Purdue Memorial Unionbus
6h$497–1,226Bus
cheapest- Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus Greyhound US0164 / ...
- Take the bus from Pittsburgh Intermodal Station to Lafayette Bus Stopbus FlixBus N2642 / ...
13h 55m$96–167Train
- Take the train from FREDERICK MARC eb to Washington Union Stationtrain Marc
- Take the train from Washington Union Station to Lafayette Amtrak Stationtrain Cardinal
23h 2m$252–562Drive 579.1 mi
- Drive from Frederick to West Lafayettecar 579.1 mi
10h 19m$106–153Train to Ronald Reagan Washington National Airport, fly to Indianapolis, bus
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Indianapolis (IND)plane DCA - IND
- Take the bus from Indianapolis Airport to Purdue Memorial Unionbus
6h 59m$985–1,657Bus to Washington Dulles International Airport, fly to Indianapolis, bus
- Take the bus from Frederick Transit Station to Market St & Harrison Stbus
- Fly from Washington Dulles International Airport (IAD) to Indianapolis (IND)plane IAD - IND
- Take the bus from Indianapolis Airport to Purdue Memorial Unionbus
7h 1m$117–545Bus to Baltimore-Washington International Airport, fly to Chicago Midway International Airport, train
- Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
- Fly from Baltimore-Washington International Airport (BWI) to Chicago Midway International Airport (MDW)plane BWI - MDW
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain
8h 52m$229–474Train to Ronald Reagan Washington National Airport, fly to Chicago Midway International Airport, train
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Chicago Midway International Airport (MDW)plane DCA - MDW
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain
9h 43m$157–705
Frederick to West Lafayette by bus
Questions & Answers
The cheapest way to get from Frederick to West Lafayette is to bus which costs $95 - $170 and takes 13h 55m.
The fastest way to get from Frederick to West Lafayette is to bus and fly which takes 6h and costs $490 - $1,300.
No, there is no direct bus from Frederick station to West Lafayette. However, there are services departing from Frederick Bus Station and arriving at Lafayette Bus Stop via Pittsburgh Intermodal Station. The journey, including transfers, takes approximately 13h 55m.
No, there is no direct train from Frederick to West Lafayette station. However, there are services departing from FREDERICK MARC eb and arriving at Lafayette Amtrak Station via Washington Union Station. The journey, including transfers, takes approximately 23h 2m.
The distance between Frederick and West Lafayette is 637 miles. The road distance is 582.5 miles.
The best way to get from Frederick to West Lafayette without a car is to bus which takes 13h 55m and costs $95 - $170.
It takes approximately 6h to get from Frederick to West Lafayette, including transfers.
Frederick to West Lafayette bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Frederick to West Lafayette train services, operated by Maryland Transit, depart from FREDERICK MARC eb station.
The best way to get from Frederick to West Lafayette is to bus which takes 13h 55m and costs $95 - $170. Alternatively, you can train, which costs $250 - $600 and takes 23h 2m.
What companies run services between Frederick, MD, USA and West Lafayette, IN, USA?
You can take a bus from Frederick Bus Station to Lafayette Bus Stop via Pittsburgh Intermodal Station in around 13h 55m. Alternatively, you can take a train from FREDERICK MARC eb to Lafayette Amtrak Station via Washington Union Station in around 23h 2m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Indianapolis
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $100–600
Flights from Baltimore-Washington International Airport to Indianapolis via Nashville
- Ave. Duration
- 4h 10m
- When
- Sunday and Saturday
- Estimated price
- $140–700
Flights from Baltimore-Washington International Airport to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 4h 25m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $130–700
Flights from Ronald Reagan Washington National Airport to Indianapolis via Chicago Midway International Airport
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Baltimore-Washington International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $75–410
Flights from Baltimore-Washington International Airport to Chicago Midway International Airport via Columbus
- Ave. Duration
- 3h 40m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $75–410
Flights from Baltimore-Washington International Airport to Chicago Midway International Airport via Pittsburgh
- Ave. Duration
- 3h 45m
- When
- Tuesday and Wednesday
- Estimated price
- $75–410
Flights from Ronald Reagan Washington National Airport to Chicago Midway International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $110–600
Flights from Ronald Reagan Washington National Airport to Chicago Midway International Airport via Columbus
- Ave. Duration
- 4h 20m
- When
- Saturday
- Estimated price
- $110–600
- Website
- delta.com
Flights from Baltimore-Washington International Airport to Indianapolis via Detroit
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $120–650
Flights from Ronald Reagan Washington National Airport to Indianapolis via Detroit
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $170–900
Flights from Washington Dulles International Airport to Indianapolis via Detroit
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Baltimore-Washington International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $80–420
Flights from Ronald Reagan Washington National Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $110–650
- Website
- aa.com
Flights from Ronald Reagan Washington National Airport to Indianapolis
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $150–850
Flights from Ronald Reagan Washington National Airport to Indianapolis via Charlotte
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Ronald Reagan Washington National Airport to Indianapolis via Philadelphia
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $180–950
Flights from Washington Dulles International Airport to Indianapolis via Charlotte
- Ave. Duration
- 3h 58m
- When
- Sunday
- Estimated price
- $110–600
- Website
- united.com
Flights from Washington Dulles International Airport to Indianapolis
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $85–480
- Phone
- 1-866-743-3682
- Website
- mta.maryland.gov
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–12
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–10
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–10
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Washington Union Station to Lafayette Amtrak Station
- Ave. Duration
- 20h 22m
- Frequency
- 3 times a week
- Estimated price
- $250–550
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $35–80
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $35–80
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 410-912-6000
- [email protected]
- Website
- bayrunnershuttle.com
Bus from Frederick Bayrunner Office to Baltimore Airport
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $65–90
- Schedules at
- bayrunnershuttle.com
Bus from Frederick Bayrunner Office to Baltimore Airport
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $65–90
- Schedules at
- bayrunnershuttle.com
- Phone
- +1 765-637-5124
- [email protected]
- Website
- reindeershuttle.com
Bus from Indianapolis Airport to Purdue Memorial Union
- Ave. Duration
- 1h 15m
- Frequency
- Every 4 hours
- Estimated price
- $28–36
- Website
- https://www.reindeershuttle.com
- Online Advance
- $28–31
- Walk up Cash
- $33–36
Bus from Indianapolis Airport to Purdue Memorial Union
- Ave. Duration
- 1h 15m
- Frequency
- Every 4 hours
- Estimated price
- $28–36
- Website
- https://www.reindeershuttle.com
- Online Advance
- $28–31
- Walk up Cash
- $33–36
Bus from Indianapolis Airport to Purdue Memorial Union
- Ave. Duration
- 1h 15m
- Frequency
- Every 4 hours
- Estimated price
- $28–36
- Website
- https://www.reindeershuttle.com
- Online Advance
- $28–31
- Walk up Cash
- $33–36
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Frederick Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Pittsburgh Intermodal Station to Lafayette Bus Stop
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $65–110
- Schedules at
- flixbus.com
- Phone
- +1 703-771-5665
- Website
- loudoun.gov
Bus from Frederick Transit Station to Market St & Harrison St
- Ave. Duration
- 58 min
- Frequency
- Once daily
- Estimated price
- $1–11
- Schedules at
- loudoun.gov
- Local & Metro
- $1–2
- Commuter
- $11
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More Questions & Answers
Frederick to West Lafayette bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Frederick to West Lafayette train services, operated by Maryland Transit, arrive at Washington Union Station.
Yes, the driving distance between Frederick to West Lafayette is 583 miles. It takes approximately 10h 19m to drive from Frederick to West Lafayette.
Book your Frederick to West Lafayette bus tickets online with Omio and FlixBus.
There are 50+ hotels available in West Lafayette.















