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How to get fromFresno to Knoxvilleby plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 8 ways to get from Fresno to Knoxville by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Fresno Yosemite International Airport to Mcghee Tyson Airport

    best
    1. Fly from Fresno Yosemite International Airport (FAT) to Mcghee Tyson Airport (TYS)plane plane FAT - TYS
    8h 30m
    $316–1,171

  2. Fly Fresno Yosemite International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Fresno Yosemite International Airport (FAT) to Asheville Regional Airport (AVL)plane plane FAT - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    10h 28m
    $173–636

  3. Bus, train

    1. Take the bus from Fresno Bus Station to Los Angeles Union Stationbus bus
    2. Take the train from Los Angeles to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus
    3d 11h
    $1,228–2,470

  4. Bus

    1. Take the bus from Fresno Bus Station to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    4. Take the bus from New York to Knoxvillebus bus
    3d 12h
    $698–1,240

  5. Drive 2,290.7 mi

    1. Drive from Fresno to Knoxvillecar car 2,290.7 mi
    36h 26m
    $419–604

  6. Fly Fresno Yosemite International Airport to Chattanooga Metropolitan Airport, drive

    1. Fly from Fresno Yosemite International Airport (FAT) to Chattanooga Metropolitan Airport (CHA)plane plane FAT - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    9h 53m
    $279–1,129

  7. Bus to Meadows Field Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Fresno to Bakersfieldbus bus
    2. Fly from Meadows Field Airport (BFL) to Mcghee Tyson Airport (TYS)plane plane BFL - TYS
    9h 52m
    $398–1,333

  8. Bus, train via Anaheim

    1. Take the bus from Fresno to Los Angelesbus bus
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus
    3d 12h
    $1,235–2,440

Fresno Yosemite International Airport (FAT) to Mcghee Tyson Airport (TYS) flights

Calendar31Weekly Planes
Duration7h 27mAverage Duration
Ticket$264Cheapest Price
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Questions & Answers

Map of how to get from Fresno to Knoxville.ExpandLaunch map view
  • Distance: 2,000.2 mi
  • Duration: 8h 30m

What companies run services between Fresno, CA, USA and Knoxville, TN, USA?

American Airlines, United Airlines, and Southwest Airlines fly from Fresno Yosemite International Airport (FAT) to Mcghee Tyson Airport (TYS) 4 times a day. Alternatively, you can take a bus from Fresno Bus Station to Knoxville via Los Angeles Union Station, St Louis Bus Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 3d 12h.

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