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How to get fromFrosinone to Sienaby bus, train (Trenitalia), or car

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There are 5 ways to get from Frosinone to Siena by bus, train (Trenitalia), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from FROSINONE | Via Monti Lepini Via Calvosa # f5860 to ROMA | Stazione Tiburtina FS # f15052bus bus So780a
    2. Take the bus from Roma, Autostazione Tiburtina to Sienabus bus 1520
    4h 54m
    €25–41

  2. Bus via Rome

    cheapest
    1. Take the bus from FROSINONE | Via Moro Via Piave # f3475 to ROMA | Anagninabus bus Fr248a / ...
    2. Take the bus from Roma - Via Vincenzo Giudice to Sienabus bus
    6h 42m
    €24–29

  3. Train (Trenitalia)

    1. Take the train from Frosinone to Firenze S.M.N.train train Fr
    2. Take the train from Firenze S.M.N. to Sienatrain train Re
    5h 54m
    €57–97

  4. Drive  296.3 km

    1. Drive from Frosinone to Sienacar car 296.3 km
    2h 49m
    €54–77

  5. Train via Rome (Trenitalia)

    1. Take the train from Frosinone to Roma Terminitrain train Re
    2. Take the train from Roma Termini to Chiusi-Chianciano T.train train
    3. Take the train from Chiusi-Chianciano T. to Sienatrain train Re
    7h 11m
    €36–65

Frosinone to Siena by bus

Calendar7Weekly Buses
Duration4h 54mAverage Duration
Ticket€25Cheapest Price
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Comparing Your Travel Options

Map of how to get from Frosinone to Siena.ExpandLaunch map view
  • Distance: 313.8 km
  • Duration: 4h 54m

What companies run services between Frosinone, Lazio, Italy and Siena, Italy?

You can take a bus from FROSINONE | Via Monti Lepini Via Calvosa # f5860 to Siena via ROMA | Stazione Tiburtina FS # f15052 and Roma, Autostazione Tiburtina in around 4h 54m. Alternatively, you can take a bus from FROSINONE | via Vado del Tufo # f99935 to Siena via FROSINONE | Frasca # f99936, Frosinone, and Firenze S.M.N. in around 5h 54m.

Train operators
Bus operators

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