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How to get fromFrosinone to Sienaby train (Trenitalia), bus, car, train, or plane

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There are 6 ways to get from Frosinone to Siena by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Frosinone to Firenze S.M.N.train train Fr
    2. Take the train from Firenze S.M.N. to Sienatrain train Re
    4h 24m
    €61–118

  2. Bus

    cheapest
    1. Take the bus from FROSINONE | Via Monti Lepini Via Calvosa # f5860 to ROMA | Stazione Tiburtina FS # f15052bus bus So780a
    2. Take the bus from Roma, Autostazione Tiburtina to Sienabus bus 1520
    4h 54m
    €22–35

  3. Drive 296.3 km

    1. Drive from Frosinone to Sienacar car 296.3 km
    2h 49m
    €47–67

  4. Train, fly

    1. Take the train from Frosinone to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane plane FCO - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 18m
    €86–243

  5. Bus via Rome

    1. Take the bus from Frosinone to Anagninabus bus
    2. Take the bus from Roma - Via Vincenzo Giudice to Sienabus bus
    6h 11m
    €25–29

  6. Train via Rome (Trenitalia)

    1. Take the train from Frosinone to Roma Terminitrain train Re
    2. Take the train from Roma Termini to Chiusi-Chianciano T.train train
    3. Take the train from Chiusi-Chianciano T. to Sienatrain train Re
    6h 20m
    €37–79

Frosinone to Siena by train (Trenitalia)

Calendar14Weekly Trains
Duration4h 24mAverage Duration
Ticket€61Cheapest Price
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Questions & Answers

Map of how to get from Frosinone to Siena.ExpandLaunch map view
  • Distance: 436.7 km
  • Duration: 4h 24m

What companies run services between Frosinone, Lazio, Italy and Siena, Italy?

You can take a train from Frosinone to Siena via Firenze S.M.N. in around 4h 24m. Alternatively, you can take a bus from FROSINONE | Via Monti Lepini Via Calvosa # f5860 to Siena via ROMA | Stazione Tiburtina FS # f15052 and Roma, Autostazione Tiburtina in around 4h 54m.

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