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How to get fromGainesville to Buffaloby bus, plane, bus (Greyhound), train, car, or train (Amtrak)

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There are 6 ways to get from Gainesville to Buffalo by bus, plane, bus (Greyhound), train, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Buffalo Niagara International Airport (BUF)plane plane ATL - BUF
    5h 23m
    $74–341

  2. Bus (Greyhound)

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Buffalobus bus
    25h 3m
    $169–329

  3. Train, bus

    1. Take the train from Gainesville Station to Ny Moynihan Train Hall At Penn Stationtrain train Crescent
    2. Take the bus from New York Midtown to Buffalobus bus FlixBus N2686 / ...
    27h 43m
    $333–653

  4. Drive 809.2 mi

    1. Drive from Gainesville to Buffalocar car 809.2 mi
    14h 41m
    $148–214

  5. Bus, fly to Rochester

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Rochester (ROC)plane plane ATL - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 6m
    $201–876

  6. Train (Amtrak)

    1. Take the train from Gainesville Station to Ny Moynihan Train Hall At Penn Stationtrain train Crescent
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    27h 53m
    $403–823

Gainesville to Buffalo by train and bus

Calendar7Weekly Services
Duration27h 43mAverage Duration
Ticket$333Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Buffalo.ExpandLaunch map view
  • Distance: 791.1 mi
  • Duration: 5h 23m

What companies run services between Gainesville, GA, USA and Buffalo, NY, USA?

You can take a vehicle from Gainesville to Buffalo via Gainesville, Atlanta Bus Station, and Cleveland Bus Station in around 25h 3m. Alternatively, you can take a train from Gainesville Station to Buffalo via Ny Moynihan Train Hall At Penn Station in around 27h 53m.

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Bus operators

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