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How to get fromGainesville to Buffalo Depew Stationby bus, plane, bus (Greyhound), train (Amtrak), car, or train

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There are 6 ways to get from Gainesville to Buffalo Depew Station by bus, plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Buffalo Niagara International Airport

    best
    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Buffalo Niagara International Airport (BUF)plane plane ATL - BUF
    4h 35m
    $123–326

  2. Bus (Greyhound)

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Buffalobus bus
    27h 16m
    $172–323

  3. Train (Amtrak)

    1. Take the train from Gainesville Station to Ny Moynihan Train Hall At Penn Stationtrain train Crescent
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalo Depew Stationtrain train Empire Service / ...
    27h 19m
    $380–805

  4. Drive 812.3 mi

    1. Drive from Gainesville to Buffalo Depew Stationcar car 812.3 mi
    14h 42m
    $149–215

  5. Bus, fly to Rochester, train

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Rochester (ROC)plane plane ATL - ROC
    3. Take the train from Rochester to Buffalo Depew Stationtrain train
    6h 43m
    $206–1,064

  6. Train via New York

    1. Take the train from Gainesville Station to Ny Moynihan Train Hall At Penn Stationtrain train Crescent
    2. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    27h 27m
    $360–815

Gainesville to Buffalo Depew Station by train (Amtrak)

Calendar7Weekly Trains
Duration27h 19mAverage Duration
Ticket$380Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Buffalo Depew Station.ExpandLaunch map view
  • Distance: 779.6 mi
  • Duration: 4h 35m

What companies run services between Gainesville, GA, USA and Buffalo Depew Station, NY, USA?

You can take a vehicle from Gainesville to Buffalo Depew Station via Gainesville, Atlanta Bus Station, Cleveland Bus Station, Ellicott Street & MTC Static, Walden Avenue & Thruway Transit Center, and Walden Avenue & 2929 Walden Avenue in around 27h 16m. Alternatively, you can take a train from Gainesville Station to Buffalo Depew Station via Ny Moynihan Train Hall At Penn Station in around 27h 19m.

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