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How to get fromGainesville to Des Moinesby bus, plane, bus (Greyhound, Flixbus), car, or bus (Flixbus, Amtrak, Greyhound)

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There are 4 ways to get from Gainesville to Des Moines by bus, plane, bus (Greyhound, Flixbus), car, or bus (Flixbus, Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly

    best
    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Des Moines (DSM)plane plane ATL - DSM
    4h 49m
    $189–853

  2. Bus

    cheapest
    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    23h 18m
    $159–309

  3. Drive 886.3 mi

    1. Drive from Gainesville to Des Moinescar car 886.3 mi
    16h 17m
    $162–234

  4. Bus via Carbondale

    1. Take the bus from BB Wireless - Gainesville to Atlantabus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale to St. Louisbus bus
    4. Take the bus from St Louis Bus Station to Des Moinesbus bus
    23h 33m
    $193–430

Hartsfield-Jackson Atlanta International Airport (ATL) to Des Moines (DSM) flights

Calendar74Weekly Planes
Duration4h 6mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Des Moines.ExpandLaunch map view
  • Distance: 812.6 mi
  • Duration: 4h 49m

What companies run services between Gainesville, GA, USA and Des Moines, IA, USA?

You can take a vehicle from Gainesville to Des Moines via Gainesville, Atlanta Bus Station, and St Louis Bus Station in around 23h 18m.

Airlines
Bus operators

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