Rome2Rio

How to get fromGainesville to Florenceby bus (Greyhound), train, bus, car, plane, or train (Amtrak)

Find Transport to Florence

See all options

There are 5 ways to get from Gainesville to Florence by bus (Greyhound), train, bus, car, plane, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus Greyhound US0670
    2. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus Greyhound US0641S / ...
    8h 28m
    $59–114

  2. Drive 269.6 mi

    cheapest
    1. Drive from Gainesville to Florencecar car 269.6 mi
    4h 53m
    $50–72

  3. Train, bus

    1. Take the train from Gainesville Station to Charlotte Amtrak Stationtrain train
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    9h 48m
    $87–180

  4. Bus, fly, train

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Fayetteville Municipal Airport (FAY)plane plane ATL - FAY
    3. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    6h 44m
    $119–476

  5. Train (Amtrak)

    1. Take the train from Gainesville Station to Charlotte Amtrak Stationtrain train
    2. Take the train from Charlotte Amtrak Station to Selma Stationtrain train
    3. Take the train from Selma Station to Florence Stationtrain train
    13h 23m
    $165–367

Gainesville to Florence by train, foot, tram, and bus

Calendar7Weekly Services
Duration9h 48mAverage Duration
Ticket$87Cheapest Price
See schedules

Questions & Answers

Map of how to get from Gainesville to Florence.ExpandLaunch map view
  • Distance: 353.5 mi
  • Duration: 8h 28m

What companies run services between Gainesville, GA, USA and Florence, SC, USA?

You can take a vehicle from Gainesville to Florence Bus Station via Gainesville and Atlanta Bus Station in around 8h 28m. Alternatively, you can take a train from Gainesville Station to Florence Station via Charlotte Amtrak Station and Selma Station in around 13h 23m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers