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How to get fromGainesville to Indianapolisby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus (Greyhound)

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There are 5 ways to get from Gainesville to Indianapolis by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly

    best
    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Indianapolis (IND)plane plane ATL - IND
    4h 58m
    $154–1,034
  2. Drive 481.9 mi

    cheapest
    1. Drive from Gainesville to Indianapoliscar car 481.9 mi
    10h 6m
    $88–127
  3. Bus

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus Greyhound US0670
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    13h 48m
    $109–189
  4. Train (Amtrak)

    1. Take the train from Gainesville Station to Charlottesvilletrain train Crescent
    2. Take the train from Charlottesville to Indianapolistrain train Cardinal
    26h 53m
    $342–711
  5. Bus via Indianapolis Union Station (Greyhound)

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus Greyhound US0670
    2. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus Greyhound US0100
    13h 58m
    $99–189

Gainesville to Indianapolis by train (Amtrak)

Calendar3Weekly Trains
Duration26h 53mAverage Duration
Ticket$342Cheapest Price
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Questions & Answers

What companies run services between Gainesville, GA, USA and Indianapolis, IN, USA?

You can take a vehicle from Gainesville to Indianapolis via Gainesville and Atlanta Bus Station in around 13h 48m. Alternatively, you can take a train from Gainesville Station to Indianapolis via Charlottesville in around 26h 53m.

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