There are 4 ways to get from Gainesville to Knoxville by car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive 164.6 mi
best- Drive from Gainesville to Knoxvillecar 164.6 mi
3h 48m$30–44Bus, fly to Mcghee Tyson Airport
- Take the bus from Gainesville to Atlanta Bus Stationbus
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Mcghee Tyson Airport (TYS)plane ATL - TYS
3h 40m$157–702Bus, fly to Chattanooga Metropolitan Airport, drive
- Take the bus from Gainesville to Atlanta Bus Stationbus
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Chattanooga Metropolitan Airport (CHA)plane ATL - CHA
- Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar
5h 2m$115–660Bus, fly to Asheville Regional Airport, drive
- Take the bus from Gainesville to Atlanta Bus Stationbus
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Asheville Regional Airport (AVL)plane ATL - AVL
- Drive from Asheville-Airport-AVL to Knoxvillecar
5h 35m$89–397
Hartsfield-Jackson Atlanta International Airport (ATL) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Gainesville to Knoxville is to drive which costs $30 - $45 and takes 3h 48m.
The fastest way to get from Gainesville to Knoxville is to bus and fly which takes 3h 40m and costs $150 - $700.
The distance between Gainesville and Knoxville is 166 miles. The road distance is 165.6 miles.
It takes approximately 3h 48m to drive 165.6 miles from Gainesville to Knoxville.
Yes, the driving distance between Gainesville to Knoxville is 166 miles. It takes approximately 3h 48m to drive from Gainesville to Knoxville.
There are 286+ hotels available in Knoxville.
What companies run services between Gainesville, GA, USA and Knoxville, TN, USA?
You can drive from Gainesville to Knoxville in around 3h 48m.
- Website
- delta.com
Flights from Hartsfield-Jackson Atlanta International Airport to Mcghee Tyson Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- $80–600
Flights from Hartsfield-Jackson Atlanta International Airport to Chattanooga Metropolitan Airport
- Ave. Duration
- 56 min
- When
- Every day
- Estimated price
- $75–600
Flights from Hartsfield-Jackson Atlanta International Airport to Asheville Regional Airport
- Ave. Duration
- 1h 1m
- When
- Every day
- Estimated price
- $45–330
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Gainesville to Atlanta Bus Station
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Gainesville to Atlanta Bus Station
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Gainesville to Atlanta Bus Station
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $8–16
- Website
- Greyhound
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