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How to get fromGainesville to North Charlestonby bus, plane, bus (Greyhound), train (Amtrak), car, or train

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There are 8 ways to get from Gainesville to North Charleston by bus, plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Charleston International Airport

    best
    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Charleston International Airport (CHS)plane plane ATL - CHS
    4h 41m
    $354–1,034

  2. Drive 271.2 mi

    cheapest
    1. Drive from Gainesville to North Charlestoncar car 271.2 mi
    5h 55m
    $50–72

  3. Bus via Charlotte (Greyhound)

    1. Take the bus from Gainesville to Charlotte Bus Stationbus bus Greyhound US0670
    2. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus Greyhound US0643S
    10h 53m
    $81–158

  4. Train (Amtrak)

    1. Take the train from Gainesville Station to Charlotte Amtrak Stationtrain train
    2. Take the train from Charlotte Amtrak Station to Selma Stationtrain train
    3. Take the train from Selma Station to Charleston Amtrak Stationtrain train
    15h 1m
    $195–426

  5. Bus, fly to Savannah, train

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Savannah (SAV)plane plane ATL - SAV
    3. Take the train from Savannah Station to Charleston Amtrak Stationtrain train
    6h 17m
    $332–702

  6. Bus, fly to Myrtle Beach

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Myrtle Beach (MYR)plane plane ATL - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    7h 7m
    $277–724

  7. Train, bus

    1. Take the train from Gainesville Station to Charlotte Amtrak Stationtrain train Crescent
    2. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus Greyhound US0643S
    12h 28m
    $109–227

  8. Bus

    1. Take the bus from BB Wireless - Gainesville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    14h 2m
    $113–285

Gainesville to North Charleston by train (Amtrak)

Calendar7Weekly Trains
Duration15h 1mAverage Duration
Ticket$195Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to North Charleston.ExpandLaunch map view
  • Distance: 331.7 mi
  • Duration: 4h 41m

What companies run services between Gainesville, GA, USA and North Charleston, SC, USA?

You can take a vehicle from Gainesville to Charleston Bus Station via Gainesville and Charlotte Bus Station in around 10h 53m. Alternatively, you can take a train from Gainesville Station to Charleston Amtrak Station via Charlotte Amtrak Station and Selma Station in around 15h 1m.

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