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How to get fromGainesville to Knoxvilleby bus, plane, train, car, or bus (Flixbus)

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There are 9 ways to get from Gainesville to Knoxville by bus, plane, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Ronald Reagan Washington National Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from Heathcote Blvd @ Trek Way to Wilson Blvd @ N Kent Stbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane plane DCA - TYS
    4h 15m
    $248–1,184

  2. Drive 442.3 mi

    cheapest
    1. Drive from Gainesville to Knoxvillecar car 442.3 mi
    7h 42m
    $81–117

  3. Bus, train via Farragut

    1. Take the bus from Heathcote Blvd @ Trek Way to N Fairfax Dr @ N Lincoln Stbus bus 622
    2. Take the train from New Carrollton Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    19h 8m
    $261–407

  4. Bus to Washington Dulles International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Heathcote Blvd @ Trek Way to N Fairfax Dr @ N Lincoln Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Mcghee Tyson Airport (TYS)plane plane IAD - TYS
    4h 15m
    $168–734

  5. Bus to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Heathcote Blvd @ Trek Way to N Fairfax Dr @ N Lincoln Stbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane plane BWI - TYS
    5h 7m
    $200–892

  6. Bus to Ronald Reagan Washington National Airport, fly to Asheville Regional Airport, drive

    1. Take the bus from Heathcote Blvd @ Trek Way to Wilson Blvd @ N Kent Stbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Asheville Regional Airport (AVL)plane plane DCA - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    5h 55m
    $120–599

  7. Bus, train

    1. Take the bus from Heathcote Blvd @ Trek Way to N Fairfax Dr @ N Lincoln Stbus bus 622
    2. Take the train from New Carrollton Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    19h 12m
    $216–317

  8. Bus via Washington

    1. Take the bus from Heathcote Blvd @ Trek Way to N Fairfax Dr @ N Lincoln Stbus bus 622
    2. Take the bus from Washington Union Station to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    20h 2m
    $237–338

  9. Bus

    1. Take the bus from Heathcote Blvd @ Trek Way to Wilson Blvd @ N Kent Stbus bus 622
    2. Take the bus from Arlington, VA to Penn Station 7th Ave. Corner of W 30th Streetbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    20h 5m
    $239–334

Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS) flights

Calendar66Weekly Planes
Duration3h 38mAverage Duration
Ticket$184Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Knoxville.ExpandLaunch map view
  • Distance: 485.2 mi
  • Duration: 4h 15m

What companies run services between Gainesville, VA, USA and Knoxville, TN, USA?

You can take a bus from Heathcote Blvd @ Trek Way to Knoxville via N Fairfax Dr @ N Lincoln St, Virginia Square, Orange/Silver Line Track 1 Platform, Metro Center, Red Line Track 1 Platform, Union Station, Red Line Center Platform, Washington Union Station, New York Midtown, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 20h 2m.

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