Rome2Rio

How to get fromGainesville to Louisvilleby bus, plane, train, bus (Greyhound, Amtrak), or car

Find Transport to Louisville

See all options

There are 9 ways to get from Gainesville to Louisville by bus, plane, train, bus (Greyhound, Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Ronald Reagan Washington National Airport, fly to Louisville International Airport

    best
    1. Take the bus from Heathcote Blvd @ Trek Way to Wilson Blvd @ N Kent Stbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    5h 14m
    $154–867

  2. Bus to Washington Dulles International Airport, fly to Louisville International Airport

    cheapest
    1. Take the bus from Heathcote Blvd @ Trek Way to N Fairfax Dr @ N Lincoln Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Louisville International Airport (SDF)plane plane IAD - SDF
    5h 19m
    $99–567

  3. Train, bus (Amtrak)

    1. Take the train from Manassas Amtrak Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    21h 2m
    $256–523

  4. Bus

    1. Take the bus from Heathcote Blvd @ Trek Way to Wilson Blvd @ N Kent Stbus bus 622
    2. Take the bus from Washington Union Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville to Louisville, KYbus bus
    22h 11m
    $146–257

  5. Drive 548.2 mi

    1. Drive from Gainesville to Louisvillecar car 548.2 mi
    9h 23m
    $100–145

  6. Bus to Ronald Reagan Washington National Airport, fly to Blue Grass Airport, drive

    1. Take the bus from Heathcote Blvd @ Trek Way to Wilson Blvd @ N Kent Stbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Blue Grass Airport (LEX)plane plane DCA - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 5m
    $216–1,233

  7. Bus to Baltimore-Washington International Airport, fly to Louisville International Airport

    1. Take the bus from Heathcote Blvd @ Trek Way to N Fairfax Dr @ N Lincoln Stbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    6h 2m
    $116–625

  8. Bus to Ronald Reagan Washington National Airport, fly to Covington, bus

    1. Take the bus from Heathcote Blvd @ Trek Way to Wilson Blvd @ N Kent Stbus bus
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Covington (CVG)plane plane DCA - CVG
    3. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    7h 40m
    $144–1,161

  9. Bus, train

    1. Take the bus from Heathcote Blvd @ Trek Way to N Farifax Dr @ N Taylor Stbus bus 622
    2. Take the train from Alexandria to Pittsburgh Amtrak Stationtrain train
    3. Take the bus from Pittsburgh Intermodal Station to Cincinnatibus bus
    4. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    22h 29m
    $159–342

Gainesville to Louisville by bus and subway

Calendar7Weekly Services
Duration22h 11mAverage Duration
Ticket$146Cheapest Price
See schedules

Questions & Answers

Map of how to get from Gainesville to Louisville.ExpandLaunch map view
  • Distance: 515.2 mi
  • Duration: 5h 14m

What companies run services between Gainesville, VA, USA and Louisville, KY, USA?

You can take a bus from Heathcote Blvd @ Trek Way to Louisville, KY via Wilson Blvd @ N Kent St, Rosslyn, Blue/Orange/Silver Line Track 1 Platform, Foggy Bottom-GWU, Blue/Orange/Silver Line Center Platform, New Hampshire Av NW+24 St NW, Massachusetts Av NE+1 St NE, Washington Union Station, and Nashville in around 22h 11m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound