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How to get fromGainesville to Columbiaby plane, bus (Flixbus, Greyhound), car, or bus

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There are 6 ways to get from Gainesville to Columbia by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Columbia Regional Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Columbia Regional Airport (COU)plane plane GNV - COU
    7h 40m
    $152–526
  2. Fly Gainesville Regional Airport to Lambert–St. Louis International Airport, bus

    cheapest
    1. Fly from Gainesville Regional Airport (GNV) to Lambert–St. Louis International Airport (STL)plane plane GNV - STL
    2. Take the bus from St Louis Bus Station to Columbiabus bus
    10h 8m
    $136–650
  3. Bus

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Columbiabus bus
    22h 20m
    $159–301
  4. Drive 1,004.7 mi

    1. Drive from Gainesville to Columbiacar car 1,004.7 mi
    16h 52m
    $184–265
  5. Bus to Jacksonville, fly to Columbia Regional Airport

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Columbia Regional Airport (COU)plane plane JAX - COU
    9h 16m
    $162–636
  6. Drive to Orlando Sanford, fly to Columbia Regional Airport

    1. Drive from Gainesville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Columbia Regional Airport (COU)plane plane SFB - COU
    5h 20m
    $160–534

Gainesville to Columbia by bus

Calendar24Weekly Buses
Duration22h 20mAverage Duration
Ticket$159Cheapest Price
See schedules

Questions & Answers

What companies run services between Gainesville, FL, USA and Columbia, MO, USA?

American Airlines flies from Gainesville Regional Airport (GNV) to Columbia Regional Airport (COU) 3 times a day. Alternatively, you can take a bus from Gainesville to Columbia via Atlanta Bus Station and St Louis Bus Station in around 22h 20m.

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