There are 5 ways to get from Gainesville to Florence Station by bus (Flixbus), bus, train, car, plane, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Gainesville to Jacksonvillebus FlixBus 2431
- Take the bus from Jacksonville to Florencebus FlixBus N2472
8h 12m$77–123Bus via Sumter
cheapest- Take the bus from Gainesville to Jacksonvillebus
- Take the bus from Jacksonville to Sumter Bus Stopbus
- Take the bus from Sumter Bus Stop to Florence Bus Stationbus
10h 59m$61–120Bus, train
- Take the bus from Gainesville to Jacksonvillebus FlixBus 2431
- Take the train from Jacksonville to Florence Stationtrain Silver Meteor
9h 32m$112–251Drive 371.4 mi
- Drive from Gainesville to Florence Stationcar 371.4 mi
6h 21m$68–98Fly
- Fly from Gainesville Regional Airport (GNV) to Florence Regional Airport (FLO)plane GNV - FLO
5h 40m$72–354
Gainesville to Florence Station by bus and train
Questions & Answers
The cheapest way to get from Gainesville to Florence Station is to bus via Sumter which costs $60 - $120 and takes 10h 59m.
The fastest way to get from Gainesville to Florence Station is to fly which takes 5h 40m and costs $70 - $360.
No, there is no direct bus from Gainesville to Florence Station. However, there are services departing from Gainesville and arriving at Florence via Jacksonville. The journey, including transfers, takes approximately 8h 12m.
The distance between Gainesville and Florence Station is 390 miles. The road distance is 373.5 miles.
The best way to get from Gainesville to Florence Station without a car is to bus which takes 8h 12m and costs $75 - $130.
It takes approximately 8h 12m to get from Gainesville to Florence Station, including transfers.
Gainesville to Florence Station bus services, operated by Flixbus USA, depart from Gainesville station.
The best way to get from Gainesville to Florence Station is to bus which takes 8h 12m and costs $75 - $130. Alternatively, you can fly, which costs $70 - $360 and takes 5h 40m.
Gainesville to Florence Station bus services, operated by Flixbus USA, arrive at Jacksonville station.
Yes, the driving distance between Gainesville to Florence Station is 374 miles. It takes approximately 6h 21m to drive from Gainesville to Florence Station.
What companies run services between Gainesville, FL, USA and Florence Station, SC, USA?
You can take a bus from Gainesville to Florence Station via Jacksonville and Florence in around 8h 12m. Alternatively, American Airlines flies from Gainesville Regional Airport (GNV) to Florence Regional Airport (FLO) 5 times a day.
- Website
- aa.com
Flights from Gainesville Regional Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 6h 34m
- When
- Every day
- Estimated price
- $60–340
Flights from Gainesville Regional Airport to Florence Regional Airport via Miami, Charlotte
- Ave. Duration
- 7h 57m
- When
- Every day
- Estimated price
- $95–460
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jacksonville to Florence Station
- Ave. Duration
- 6h 11m
- Frequency
- Once daily
- Estimated price
- $100–230
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $10–18
- Schedules at
- Flixbus USA
Bus from Jacksonville to Florence
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $50–85
- Schedules at
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $10–18
- Schedules at
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $10–18
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Jacksonville to Sumter Bus Stop
- Ave. Duration
- 6h 10m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- Greyhound
Bus from Sumter Bus Stop to Florence Bus Station
- Ave. Duration
- 55 min
- Frequency
- Twice daily
- Estimated price
- $5–12
- Website
- Greyhound
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More Questions & Answers
There are 47+ hotels available in Florence Station.






