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How to get fromGainesville to Florida Keysby plane, car, or bus

Find Transport to Florida Keys

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There are 5 ways to get from Gainesville to Florida Keys by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Gainesville Regional Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane plane GNV - EYW
    4h 45m
    $46–272

  2. Drive 474.4 mi

    1. Drive from Gainesville to Key Westcar car 474.4 mi
    9h 22m
    $87–126

  3. Bus to Orlando, fly

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    4h 40m
    $101–708

  4. Bus to Jacksonville, fly

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane plane JAX - EYW
    7h 42m
    $372–821

  5. Drive to Orlando Sanford, fly

    1. Drive from Gainesville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3h 44m
    $55–279

Gainesville Regional Airport (GNV) to Key West International Airport (EYW) flights

Calendar40Weekly Planes
Duration4h 58mAverage Duration
Ticket$46Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Florida Keys.ExpandLaunch map view
  • Distance: 361 mi
  • Duration: 4h 45m

What companies run services between Gainesville, FL, USA and Florida Keys, Monroe County, FL, USA?

American Airlines and Delta fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW) every 4 hours.

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