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How to get fromGainesville to Iowaby plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 9 ways to get from Gainesville to Iowa by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Gainesville Regional Airport (GNV) to Des Moines (DSM)plane plane GNV - DSM
    6h 22m
    $178–822

  2. Fly to Quad City International Airport

    cheapest
    1. Fly from Gainesville Regional Airport (GNV) to Quad City International Airport (MLI)plane plane GNV - MLI
    7h 4m
    $94–444

  3. Bus via Kansas City

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    4. Take the bus from Kansas City to Des Moinesbus bus
    27h 55m
    $214–384

  4. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    46h 17m
    $534–1,125

  5. Drive 1,211.8 mi

    1. Drive from Gainesville to Des Moinescar car 1,211.8 mi
    21h 14m
    $222–320

  6. Fly to The Eastern Iowa Airport

    1. Fly from Gainesville Regional Airport (GNV) to The Eastern Iowa Airport (CID)plane plane GNV - CID
    7h 34m
    $132–502

  7. Fly to Omaha

    1. Fly from Gainesville Regional Airport (GNV) to Omaha (OMA)plane plane GNV - OMA
    6h 13m
    $156–682

  8. Bus

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    28h 5m
    $197–370

  9. Bus, train via Atlanta

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the bus from Kansas City to Des Moinesbus bus
    30h 21m
    $259–494

Gainesville to Iowa by bus

Calendar12Weekly Buses
Duration27h 55mAverage Duration
Ticket$214Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Iowa.ExpandLaunch map view
  • Distance: 1,047.8 mi
  • Duration: 6h 22m

What companies run services between Gainesville, FL, USA and Iowa, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Gainesville to Des Moines via Atlanta Bus Station, St Louis Bus Station, Kansas City Bus Station, and Kansas City in around 27h 55m.

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Train operators
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