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How to get fromGainesville to Iowaby plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 10 ways to get from Gainesville to Iowa by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Des Moines

    best
    1. Fly from Gainesville Regional Airport (GNV) to Des Moines (DSM)plane plane GNV - DSM
    5h 57m
    $168–772

  2. Fly Gainesville Regional Airport to Quad City International Airport

    cheapest
    1. Fly from Gainesville Regional Airport (GNV) to Quad City International Airport (MLI)plane plane GNV - MLI
    7h 12m
    $94–454

  3. Bus via Kansas City

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    4. Take the bus from Kansas City to Des Moinesbus bus
    27h 55m
    $206–368

  4. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    46h 17m
    $474–1,069

  5. Drive 1,211.8 mi

    1. Drive from Gainesville to Des Moinescar car 1,211.8 mi
    21h 13m
    $222–320

  6. Fly Gainesville Regional Airport to The Eastern Iowa Airport

    1. Fly from Gainesville Regional Airport (GNV) to The Eastern Iowa Airport (CID)plane plane GNV - CID
    6h 46m
    $136–512

  7. Fly Gainesville Regional Airport to Omaha

    1. Fly from Gainesville Regional Airport (GNV) to Omaha (OMA)plane plane GNV - OMA
    6h 10m
    $156–632

  8. Drive to Orlando Sanford, fly to Des Moines

    1. Drive from Gainesville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    5h 29m
    $197–800

  9. Bus

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    28h 5m
    $184–354

  10. Bus, train via Atlanta

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the bus from Kansas City to Des Moinesbus bus
    30h 21m
    $241–468

Gainesville to Iowa by bus

Calendar12Weekly Buses
Duration27h 55mAverage Duration
Ticket$206Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Iowa.ExpandLaunch map view
  • Distance: 1,047.8 mi
  • Duration: 5h 57m

What companies run services between Gainesville, FL, USA and Iowa, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Gainesville to Des Moines via Atlanta Bus Station, St Louis Bus Station, Kansas City Bus Station, and Kansas City in around 27h 55m.

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