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How to get fromGainesville to Key West (Island)by plane, bus, train, car, shuttle, bus (Flixbus, Greyhound), or ferry

Find Transport to Key West (Island)

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There are 10 ways to get from Gainesville to Key West (Island) by plane, bus, train, car, shuttle, bus (Flixbus, Greyhound), or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Gainesville Regional Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane plane GNV - EYW
    5h 10m
    $46–302

  2. Bus, train via Meadow Woods

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Key West Airportbus bus
    12h 44m
    $117–279

  3. Drive  474.4 mi

    1. Drive from Gainesville to Key Westcar car 474.4 mi
    9h 22m
    $87–126

  4. Drive to Orlando Sanford, fly

    1. Drive from Gainesville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    3h 38m
    $60–309

  5. Bus to Orlando, fly

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    4h 48m
    $101–741

  6. Bus to Jacksonville, fly

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Key West International Airport (EYW)plane plane JAX - EYW
    8h 12m
    $57–309

  7. Bus, train

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to West Palm Beach, FLbus bus
    2. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Key West Airportbus bus
    13h 1m
    $101–150

  8. Bus, shuttle

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Kissimmee -1471 East Osceola Parkwaybus bus
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Bayside Marketplacebus bus
    3. Take a shuttle bus from Bayside Marketplace to Plaza Hotelshuttle bus
    13h 25m
    $126–147

  9. Bus

    1. Take the bus from Gainesville to Miami Airport Stationbus bus FlixBus N2401 / ...
    2. Take the bus from Miami Airport Station to Key West Airportbus bus Greyhound US0720s
    13h 45m
    $82–127

  10. Bus, ferry

    1. Take the bus from Gainesville to Tampa Bus Stationbus bus
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    3. Take the ferry from Fort Myers Beach, FL to Key West, FLferry ferry
    16h
    $183–218

Gainesville to Key West (Island) by bus and train

Calendar19Weekly Services
Duration13h 1mAverage Duration
Ticket$101Cheapest Price
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Comparing Your Travel Options

Map of how to get from Gainesville to Key West (Island).ExpandLaunch map view
  • Distance: 361 mi
  • Duration: 5h 10m

What companies run services between Gainesville, FL, USA and Key West (Island), FL, USA?

American Airlines and Delta fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Gainesville to Key West Airport via Miami Airport Station in around 13h 45m.

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