There are 3 ways to get from Gainesville to Lake City by bus (Greyhound), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 6 bus, bus
best- Take the bus from Westbound SW 2nd Avenue @ SW 2nd Street to North Walmart Supercenterbus 6
- Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus Greyhound US0630
2h 24m$8–12Drive 45.8 mi
- Drive from Gainesville to Lake Citycar 45.8 mi
53 min$9–13Taxi
- Take the taxi from Gainesville to Lake Citytaxi 45.8 mi
53 min$140–180
Gainesville to Lake City by bus
Comparing Your Travel Options
The cheapest way to get from Gainesville to Lake City is to line 6 bus and bus which costs $7 - $12 and takes 2h 24m.
The fastest way to get from Gainesville to Lake City is to drive which takes 53 min and costs $8 - $13.
No, there is no direct bus from Gainesville to Lake City station. However, there are services departing from Westbound SW 2nd Avenue @ SW 2nd Street and arriving at Lake City Bus Station via Gainesville Bus Stop. The journey, including transfers, takes approximately 2h 24m.
The distance between Gainesville and Lake City is 48 miles. The road distance is 46 miles.
The best way to get from Gainesville to Lake City without a car is to line 6 bus and bus which takes 2h 24m and costs $7 - $12.
It takes approximately 2h 24m to get from Gainesville to Lake City, including transfers.
Gainesville to Lake City bus services, operated by Gainesville Regional Transit System, depart from Westbound SW 2nd Avenue @ SW 2nd Street station.
Gainesville to Lake City bus services, operated by Gainesville Regional Transit System, arrive at North Walmart Supercenter station.
Yes, the driving distance between Gainesville to Lake City is 46 miles. It takes approximately 53 min to drive from Gainesville to Lake City.
Book your Gainesville to Lake City bus tickets online with Omio.
What companies run services between Gainesville, FL, USA and Lake City, FL, USA?
You can take a bus from Westbound SW 2nd Avenue @ SW 2nd Street to Lake City Bus Station via Gainesville Bus Stop in around 2h 24m.
- Website
- Regional Transit System
Bus from Westbound SW 2nd Avenue @ SW 2nd Street to North Walmart Supercenter
- Ave. Duration
- 24 min
- Frequency
- Every 2 hours
- Estimated price
- $2
- Website
- Regional Transit System
- Child and Seniors
- $0
- Adult
- $2
- Ave. Duration
- 53 min
- Estimated price
- $140–180
Cabs 24HR
- Phone
- +1 855-374-8484
- Website
- cab24hr.com
Gainesville Cab Co.
- Phone
- +1 352-371-1515
- Website
- gainesvillemarooncab.com
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Related travel guides
Need to know: Greyhound
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Booking & Getting There
There are 28+ hotels available in Lake City.