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How to get fromGainesville to Lancasterby plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 6 ways to get from Gainesville to Lancaster by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Harrisburg International Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Harrisburg International Airport (MDT)plane plane GNV - MDT
    9h 23m
    $88–426

  2. Bus

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    23h 22m
    $147–264

  3. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the train from Jacksonville to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    24h 57m
    $319–682

  4. Drive 873.7 mi

    1. Drive from Gainesville to Lancastercar car 873.7 mi
    15h 23m
    $160–231

  5. Drive to Orlando Sanford, fly to Harrisburg International Airport

    1. Drive from Gainesville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Harrisburg International Airport (MDT)plane plane SFB - MDT
    8h 49m
    $106–453

  6. Bus to Jacksonville, fly to Philadelphia International Airport, train

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Philadelphia International Airport (PHL)plane plane JAX - PHL
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    11h 23m
    $152–385

Gainesville to Lancaster by bus and train

Calendar4Weekly Services
Duration23h 22mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Lancaster.ExpandLaunch map view
  • Distance: 845.5 mi
  • Duration: 9h 23m

What companies run services between Gainesville, FL, USA and Lancaster, PA, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Harrisburg International Airport (MDT) every 4 hours. Alternatively, you can take a bus from Gainesville to W. Chestnut & Water St. via Jacksonville, Baltimore Downtown Bus Station, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 23h 22m.

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