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How to get fromGainesville to Lexingtonby plane, bus (Flixbus, Greyhound), car, or bus

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There are 4 ways to get from Gainesville to Lexington by plane, bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Gainesville Regional Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Columbia (CAE)plane plane GNV - CAE
    4h 47m
    $170–886

  2. Drive 336.3 mi

    cheapest
    1. Drive from Gainesville to Lexingtoncar car 336.3 mi
    6h 49m
    $62–89

  3. Bus

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the bus from Jacksonville to Camdenbus bus
    3. Take the bus from Camden to Columbia, SCbus bus Nyc
    11h 25m
    $119–199

  4. Bus to Jacksonville, fly

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Columbia (CAE)plane plane JAX - CAE
    7h 29m
    $190–957

Gainesville Regional Airport (GNV) to Columbia (CAE) flights

Calendar62Weekly Planes
Duration4h 41mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Lexington.ExpandLaunch map view
  • Distance: 315.4 mi
  • Duration: 4h 47m

What companies run services between Gainesville, FL, USA and Lexington, SC, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Columbia (CAE) every 3 hours. Alternatively, you can take a bus from Gainesville to Lexington via Jacksonville, Camden, and Columbia, SC in around 11h 25m.

Airlines
Bus operators

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