There are 9 ways to get from Gainesville to Louisville by plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Gainesville Regional Airport to Louisville International Airport
best- Fly from Gainesville Regional Airport (GNV) to Louisville International Airport (SDF)plane GNV - SDF
6h 45m$112–654Fly Gainesville Regional Airport to Blue Grass Airport, drive
cheapest- Fly from Gainesville Regional Airport (GNV) to Blue Grass Airport (LEX)plane GNV - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
6h 16m$80–400Bus
- Take the bus from Gainesville to Atlanta Bus Stationbus FlixBus N2415 / ...
- Take the bus from Atlanta Bus Station to Louisville Bus Stationbus Greyhound US0105 / ...
16h 15m$110–184Drive 704 mi
- Drive from Gainesville to Louisvillecar 704 mi
13h$129–186Bus to Orlando, fly to Louisville International Airport
- Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus
- Fly from Orlando (MCO) to Louisville International Airport (SDF)plane MCO - SDF
6h 47m$422–844Drive to Orlando Sanford, fly to Blue Grass Airport, drive
- Drive from Gainesville to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Blue Grass Airport (LEX)plane SFB - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
5h 39m$103–438Bus to Jacksonville, fly to Louisville International Airport
- Take the bus from Gainesville to Jacksonvillebus
- Fly from Jacksonville (JAX) to Louisville International Airport (SDF)plane JAX - SDF
8h 46m$112–671Drive to Orlando Sanford, fly to Louisville International Airport
- Drive from Gainesville to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Louisville International Airport (SDF)plane SFB - SDF
5h 43m$141–732Bus via Gainesville Bus Stop
- Take the bus from Gainesville Bus Stop to Atlanta Bus Stationbus Greyhound US0630
- Take the bus from Atlanta Bus Station to Louisville Bus Stationbus Greyhound US0105 / ...
18h 59m$112–196
Gainesville to Louisville by bus
Comparing Your Travel Options
The cheapest way to get from Gainesville to Louisville is to bus which costs $110 - $190 and takes 16h 15m.
The fastest way to get from Gainesville to Louisville is to drive and fly which takes 5h 39m and costs $100 - $440.
No, there is no direct bus from Gainesville to Louisville station. However, there are services departing from Gainesville and arriving at Louisville Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 16h 15m.
The distance between Gainesville and Louisville is 635 miles. The road distance is 708.1 miles.
The best way to get from Gainesville to Louisville without a car is to bus which takes 16h 15m and costs $110 - $190.
It takes approximately 6h 45m to get from Gainesville to Louisville, including transfers.
Gainesville to Louisville bus services, operated by Flixbus USA, depart from Gainesville station.
The best way to get from Gainesville to Louisville is to fly which takes 6h 45m and costs $110 - $700. Alternatively, you can bus, which costs $110 - $190 and takes 16h 15m.
Gainesville to Louisville bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Gainesville to Louisville is 708 miles. It takes approximately 13h to drive from Gainesville to Louisville.
What companies run services between Gainesville, FL, USA and Louisville, KY, USA?
Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Louisville International Airport (SDF) every 2 hours. Alternatively, you can take a bus from Gainesville to Louisville Bus Station via Atlanta Bus Station in around 16h 15m.
- Website
- delta.com
Flights from Gainesville Regional Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $110–650
Flights from Gainesville Regional Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $65–380
Flights from Orlando to Louisville International Airport
- Ave. Duration
- 2h 23m
- When
- Saturday
- Estimated price
- $120–650
Flights from Orlando to Louisville International Airport via Atlanta
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $120–700
Flights from Jacksonville to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $100–650
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Gainesville to Atlanta Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- 4 times a day
- Estimated price
- $50–75
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Louisville Bus Station
- Ave. Duration
- 8h 15m
- Frequency
- Twice daily
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $10–16
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Louisville Bus Station
- Ave. Duration
- 8h 15m
- Frequency
- Twice daily
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
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Booking & Getting There
Book your Gainesville to Louisville bus tickets online with Omio and FlixBus.
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