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How to get fromGainesville to Mayo Clinicby plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 9 ways to get from Gainesville to Mayo Clinic by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Rochester

    best
    1. Fly from Gainesville Regional Airport (GNV) to Rochester (RST)plane plane GNV - RST
    10h 22m
    $102–522

  2. Bus

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    32h 33m
    $244–390

  3. Bus, train via Madison

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    2d
    $937–1,549

  4. Drive  1,329.7 mi

    1. Drive from Gainesville to Mayo Cliniccar car 1,329.7 mi
    22h 48m
    $243–351

  5. Fly Gainesville Regional Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Gainesville Regional Airport (GNV) to Minneapolis–Saint Paul International Airport (MSP)plane plane GNV - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 42m
    $172–652

  6. Bus to Jacksonville, fly to Rochester

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Rochester (RST)plane plane JAX - RST
    11h 30m
    $108–509

  7. Bus to Jacksonville, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Minneapolis–Saint Paul International Airport (MSP)plane plane JAX - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    10h 24m
    $182–669

  8. Bus to Orlando, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to Minneapolis–Saint Paul International Airport (MSP)plane plane MCO - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    10h 5m
    $281–1,191

  9. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    2d 1h
    $1,110–1,809

Gainesville to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration32h 33mAverage Duration
Ticket$244Cheapest Price
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Comparing Your Travel Options

Map of how to get from Gainesville to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,146 mi
  • Duration: 10h 22m

What companies run services between Gainesville, FL, USA and Mayo Clinic, MN, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Gainesville to Mayo Clinic via Atlanta Bus Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 32h 33m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

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