Rome2Rio

How to get fromGainesville to Missouriby plane, bus (Flixbus, Greyhound), car, bus, or train

Find Transport to Missouri

See all options

There are 8 ways to get from Gainesville to Missouri by plane, bus (Flixbus, Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Lambert–St. Louis International Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Lambert–St. Louis International Airport (STL)plane plane GNV - STL
    5h 57m
    $104–604

  2. Fly Gainesville Regional Airport to Springfield-Branson National Airport

    cheapest
    1. Fly from Gainesville Regional Airport (GNV) to Springfield-Branson National Airport (SGF)plane plane GNV - SGF
    5h 46m
    $98–452

  3. Bus

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    22h 26m
    $177–297

  4. Drive  1,082.5 mi

    1. Drive from Gainesville to Kansas Citycar car 1,082.5 mi
    19h 42m
    $198–286

  5. Fly Gainesville Regional Airport to Kansas City

    1. Fly from Gainesville Regional Airport (GNV) to Kansas City (MCI)plane plane GNV - MCI
    7h 22m
    $142–702

  6. Bus to Jacksonville, fly to Lambert–St. Louis International Airport

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL)plane plane JAX - STL
    6h 57m
    $115–572

  7. Bus to Orlando, fly to Lambert–St. Louis International Airport

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    6h 38m
    $214–364

  8. Bus, train

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    24h 18m
    $287–467

Gainesville to Missouri by bus

Calendar12Weekly Buses
Duration22h 26mAverage Duration
Ticket$177Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Gainesville to Missouri.ExpandLaunch map view
  • Distance: 796 mi
  • Duration: 5h 57m

What companies run services between Gainesville, FL, USA and Missouri, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Gainesville to Kansas City Bus Station via Atlanta Bus Station and St Louis Bus Station in around 22h 26m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There