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How to get fromGainesville to Mount Pleasantby bus, train, car, or plane

Find Transport to Mount Pleasant

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There are 6 ways to get from Gainesville to Mount Pleasant by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Gainesville to Jacksonvillebus bus FlixBus 2431
    2. Take the train from Jacksonville to Charleston Amtrak Stationtrain train Silver Meteor
    7h 52m
    $132–242

  2. Drive 307.4 mi

    cheapest
    1. Drive from Gainesville to Mount Pleasantcar car 307.4 mi
    5h 35m
    $57–81

  3. Fly from Gainesville Regional Airport

    1. Fly from Gainesville Regional Airport (GNV) to Charleston International Airport (CHS)plane plane GNV - CHS
    8h 8m
    $70–376

  4. Bus to Orlando, fly

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to Charleston International Airport (CHS)plane plane MCO - CHS
    7h 51m
    $100–309

  5. Bus to Jacksonville, fly

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Charleston International Airport (CHS)plane plane JAX - CHS
    10h 10m
    $86–436

  6. Bus to Tampa, fly

    1. Take the bus from Gainesville to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Charleston International Airport (CHS)plane plane TPA - CHS
    9h 5m
    $168–383

Gainesville Regional Airport (GNV) to Charleston International Airport (CHS) flights

Calendar60Weekly Planes
Duration5h 4mAverage Duration
Ticket$68Cheapest Price
See schedules

Questions & Answers

Map of how to get from Gainesville to Mount Pleasant.ExpandLaunch map view
  • Distance: 335.2 mi
  • Duration: 7h 52m

What companies run services between Gainesville, FL, USA and Mount Pleasant, SC, USA?

American Airlines and Delta fly from Gainesville Regional Airport (GNV) to Charleston International Airport (CHS) every 3 hours.

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