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How to get fromGainesville to New Orleansby plane, bus (Greyhound, Flixbus), car, bus, or train

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There are 9 ways to get from Gainesville to New Orleans by plane, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Louis Armstrong New Orleans International Airport

    best
    1. Fly from Gainesville Regional Airport (GNV) to Louis Armstrong New Orleans International Airport (MSY)plane plane GNV - MSY
    6h 47m
    $98–554

  2. Bus via Gainesville Bus Stop

    cheapest
    1. Take the bus from Gainesville Bus Stop to Tallahasseebus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    15h 29m
    $86–152

  3. Bus

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Tallahassee - FSU - Old St Augustine at Intramural Fieldbus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to New Orleans Bus Stationbus bus
    13h 44m
    $99–162

  4. Drive  530.9 mi

    1. Drive from Gainesville to New Orleanscar car 530.9 mi
    8h 41m
    $97–140

  5. Bus to Jacksonville, fly to Louis Armstrong New Orleans International Airport

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Louis Armstrong New Orleans International Airport (MSY)plane plane JAX - MSY
    7h 3m
    $97–511

  6. Bus to Orlando, fly to Louis Armstrong New Orleans International Airport

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to Louis Armstrong New Orleans International Airport (MSY)plane plane MCO - MSY
    6h 24m
    $117–444

  7. Fly Gainesville Regional Airport to Gulfport-Biloxi Regional Airport, train

    1. Fly from Gainesville Regional Airport (GNV) to Gulfport-Biloxi Regional Airport (GPT)plane plane GNV - GPT
    2. Take the train from Gulfport, MS to New Orleans, LA - Union Passenger Terminaltrain train
    7h 50m
    $134–532

  8. Bus to Tampa, fly to Louis Armstrong New Orleans International Airport

    1. Take the bus from Gainesville to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Louis Armstrong New Orleans International Airport (MSY)plane plane TPA - MSY
    8h 29m
    $107–499

  9. Bus, train

    1. Take the bus from Gainesville Bus Stop to Tallahasseebus bus
    2. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    3. Take the train from Mobile, AL to New Orleans, LA - Union Passenger Terminaltrain train
    17h 49m
    $96–232

Gainesville to New Orleans by bus

Calendar7Weekly Buses
Duration15h 29mAverage Duration
Ticket$86Cheapest Price
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Comparing Your Travel Options

Map of how to get from Gainesville to New Orleans.ExpandLaunch map view
  • Distance: 496.1 mi
  • Duration: 6h 47m

What companies run services between Gainesville, FL, USA and New Orleans, LA, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Louis Armstrong New Orleans International Airport (MSY) every 2 hours. Alternatively, you can take a bus from University of Florida - 1956 Gale Lemerand Dr to New Orleans Bus Station via Old St Augustine at Intramural Field, Tallahassee, and Mobile Bus Station in around 13h 44m.

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