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How to get fromGainesville to North Charlestonby bus, train, car, or plane

Find Transport to North Charleston

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There are 6 ways to get from Gainesville to North Charleston by bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Gainesville to Jacksonvillebus bus FlixBus 2431
    2. Take the train from Jacksonville to Charleston Amtrak Stationtrain train Silver Meteor
    7h 35m
    $142–229

  2. Drive  301.8 mi

    cheapest
    1. Drive from Gainesville to North Charlestoncar car 301.8 mi
    5h 25m
    $52–75

  3. Fly from Gainesville Regional Airport

    1. Fly from Gainesville Regional Airport (GNV) to Charleston International Airport (CHS)plane plane GNV - CHS
    6h 2m
    $78–434

  4. Bus to Orlando, fly

    1. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Orlando - RedCoach Station, FLbus bus
    2. Fly from Orlando (MCO) to Charleston International Airport (CHS)plane plane MCO - CHS
    5h 55m
    $123–303

  5. Bus to Jacksonville, fly

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Fly from Jacksonville (JAX) to Charleston International Airport (CHS)plane plane JAX - CHS
    8h 27m
    $79–421

  6. Bus to Tampa, fly

    1. Take the bus from Gainesville to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Charleston International Airport (CHS)plane plane TPA - CHS
    8h 32m
    $110–481

Gainesville to North Charleston by bus and train

Calendar7Weekly Services
Duration7h 35mAverage Duration
Ticket$142Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Gainesville to North Charleston.ExpandLaunch map view
  • Distance: 323.7 mi
  • Duration: 7h 35m

What companies run services between Gainesville, FL, USA and North Charleston, SC, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Charleston International Airport (CHS) every 3 hours.

Airlines
Train operators
Bus operators

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