There are 5 ways to get from Gainesville to Orangeburg by bus (Flixbus, Greyhound), bus, train, car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Gainesville to Jacksonvillebus FlixBus 2431
- Take the bus from Jacksonville to Orangeburgbus FlixBus 2433
6h 58m$53–85Bus, train
- Take the bus from Gainesville to Jacksonvillebus FlixBus 2431
- Take the train from Jacksonville to Denmark Amtrak Stationtrain Floridian
8h 22m$131–238Drive 302.7 mi
- Drive from Gainesville to Orangeburgcar 302.7 mi
5h 41m$56–80Fly to Columbia, taxi
- Fly from Gainesville Regional Airport (GNV) to Columbia (CAE)plane GNV - CAE
- Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi
5h 16m$176–512Fly to Augusta Regional Airport At Bush Field, drive
- Fly from Gainesville Regional Airport (GNV) to Augusta Regional Airport At Bush Field (AGS)plane GNV - AGS
- Drive from Augusta Regional Airport At Bush Field (AGS) to Orangeburgcar
6h 22m$70–372
Gainesville Regional Airport (GNV) to Columbia (CAE) flights
Comparing Your Travel Options
The cheapest way to get from Gainesville to Orangeburg is to bus which costs $50 - $85 and takes 6h 58m.
The fastest way to get from Gainesville to Orangeburg is to fly and taxi which takes 5h 16m and costs $170 - $550.
No, there is no direct bus from Gainesville to Orangeburg. However, there are services departing from Gainesville and arriving at Orangeburg via Jacksonville. The journey, including transfers, takes approximately 6h 58m.
The distance between Gainesville and Orangeburg is 318 miles. The road distance is 304.4 miles.
The best way to get from Gainesville to Orangeburg without a car is to bus which takes 6h 58m and costs $50 - $85.
It takes approximately 6h 58m to get from Gainesville to Orangeburg, including transfers.
Gainesville to Orangeburg bus services, operated by Flixbus USA, depart from Gainesville station.
Gainesville to Orangeburg bus services, operated by Flixbus USA, arrive at Jacksonville station.
Yes, the driving distance between Gainesville to Orangeburg is 304 miles. It takes approximately 5h 41m to drive from Gainesville to Orangeburg.
Book your Gainesville to Orangeburg bus tickets online with Omio.
What companies run services between Gainesville, FL, USA and Orangeburg, SC, USA?
You can take a bus from Gainesville to Orangeburg via Jacksonville and Orangeburg in around 6h 58m.
- Website
- delta.com
Flights from Gainesville Regional Airport to Columbia via Atlanta
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $60–360
Flights from Gainesville Regional Airport to Augusta Regional Airport At Bush Field via Atlanta
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $55–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Jacksonville to Denmark Amtrak Station
- Ave. Duration
- 4h 29m
- Frequency
- Once daily
- Estimated price
- $55–140
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $10–16
- Schedules at
- Flixbus USA
Bus from Jacksonville to Orangeburg
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
Bus from Gainesville to Jacksonville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $10–16
- Schedules at
- Flixbus USA
- Ave. Duration
- 42 min
- Estimated price
- $120–150
Checker Yellow Cabs
- Phone
- +1 803-799-3311
- Website
- checkeryellowcab.com
Want to know more about travelling around United States
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Booking & Getting There
There are 22+ hotels available in Orangeburg.