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How to get fromGainesville to Orangeburgby bus (Flixbus, Greyhound), bus, train, car, plane, or taxi

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There are 5 ways to get from Gainesville to Orangeburg by bus (Flixbus, Greyhound), bus, train, car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Gainesville to Jacksonvillebus bus FlixBus 2431
    2. Take the bus from Jacksonville to Orangeburgbus bus FlixBus 2433
    6h 58m
    $54–103

  2. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus bus FlixBus 2431
    2. Take the train from Jacksonville to Denmark Amtrak Stationtrain train Floridian
    8h 22m
    $152–261

  3. Drive 302.7 mi

    1. Drive from Gainesville to Orangeburgcar car 302.7 mi
    5h 41m
    $56–80

  4. Fly to Columbia, taxi

    1. Fly from Gainesville Regional Airport (GNV) to Columbia (CAE)plane plane GNV - CAE
    2. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    5h 15m
    $262–1,002

  5. Fly to Augusta Regional Airport At Bush Field, drive

    1. Fly from Gainesville Regional Airport (GNV) to Augusta Regional Airport At Bush Field (AGS)plane plane GNV - AGS
    2. Drive from Augusta Regional Airport At Bush Field (AGS) to Orangeburgcar car
    6h 26m
    $70–352

Gainesville Regional Airport (GNV) to Columbia (CAE) flights

Calendar62Weekly Planes
Duration4h 41mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from Gainesville to Orangeburg.ExpandLaunch map view
  • Distance: 315.8 mi
  • Duration: 6h 58m

What companies run services between Gainesville, FL, USA and Orangeburg, SC, USA?

You can take a bus from Gainesville to Orangeburg via Jacksonville and Orangeburg in around 6h 58m.

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